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腹横肌和腹直肌鞘阻滞联合持续静脉输注芬太尼用于腹腔镜结肠切除术后镇痛的疗效:一项回顾性研究

[Efficacy of Transversus Abdominis and Rectus Sheath Blocks in Combination with Continuous Intravenous Fentanyl for Postoperative Analgesia of Laparoscopic Colectomy: A Retrospective Study].

作者信息

Okamoto Kaori, Komasawa Nobuyasu, Kido Haruki, Kusaka Yusuke, Sawai Tosbiyuki, Minami Toshiaki

出版信息

Masui. 2017 Jan;66(1):73-75.

Abstract

BACKGROUND

Ultrasound-guided transversus ab- dominis plane (TAP) and rectus sheath (RS) blocks are peripheral nerve blocks that diminish somatic pain of the abdominal wall and are useful for postoperative analgesia. Here, we retrospectively compared the effi- cacy of ultrasound-guided TAP and RS blocks in com- bination with continuous intravenous fentanyl for postoperative analgesia of laparoscopic colectomy.

METHODS

The ethics committee of our institute ap- proved the study. In our hospital, postoperative analge- sia is performed with continuous intravenous fentanyl administration at three concentrations : 12.5, 18.75, and 31.25 μg · hr⁻¹. TAP and RS blocks were applied using 30-40 ml of 0.19-0.25% ropivacaine. We selected 43 patients who underwent laparoscopic colectomy from May to October 2015. We compared the fentanyl only group (F group, n=26) and block combination group (F+B group, n=17). Statistical analysis was performed with the Mann-Whitney U test P<0.05 was considered significant Results : Patient characteristics including age, height, body weight, duration of anesthesia, and surgery did not significantly differ between the two groups. The concentration of intravenous fentanyl was significantly lower in the F+B group than in the F group (F group : 19.5±8.4μg · hr⁻¹, F+B group : 14.7?4.9 μg · hr⁻¹, P=0.02). In the present study, TAP and RS blocks significantly reduced the dose of administered fentanyl. - Conclusions : Our findings suggest that a combina- tion of TAP and RS blocks lower the dose of continu- ous intravenous fentanyl needed, and may provide better postoperative analgesia after laparoscopic colec- tomy.

摘要

背景

超声引导下腹横肌平面(TAP)阻滞和腹直肌鞘(RS)阻滞是周围神经阻滞,可减轻腹壁的躯体疼痛,对术后镇痛有用。在此,我们回顾性比较了超声引导下TAP和RS阻滞联合持续静脉输注芬太尼用于腹腔镜结肠切除术术后镇痛的效果。

方法

我们研究所的伦理委员会批准了该研究。在我院,术后镇痛采用三种浓度(12.5、18.7 和 31.25 μg·hr⁻¹ )的持续静脉输注芬太尼。使用30 - 40 ml 0.19% - 0.25% 的罗哌卡因进行TAP和RS阻滞。我们选取了 20 15年5月至10月期间行腹腔镜结肠切除术的 43 例患者 。我们比较了单纯芬太尼组(F组,n = 26)和阻滞联合组(F + B组,n = 17)。采用曼 - 惠特尼U检验进行统计分析,P < 0.05被认为具有统计学意义。结果:两组患者包括年龄、身高、体重 , 麻醉时间和手术时间等患者特征无显著差异。F + B组静脉输注芬太尼的浓度显著低于F组(F组:19.5 ± 8.4 μg·hr⁻¹,F + B组:14.7 ± 4.9 μg·hr⁻¹,P = 0.02)。在本研究中,TAP和RS阻滞显著降低了芬太尼的给药剂量。结论:我们的研究结果表明,TAP和RS阻滞联合使用可降低所需的持续静脉输注芬太尼剂量,并可能为腹腔镜结肠切除术后提供更好的术后镇痛效果。

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