Elad Daniel
Department of Clinical Bacteriology and Mycology, The Kimron Veterinary Institute, P.O. Box 12, Bet Dagan 50250, Israel.
J Fungi (Basel). 2018 Oct 30;4(4):120. doi: 10.3390/jof4040120.
This review focuses on aspects of antimycotic therapy specific to veterinary medicine. In the first part, drug availability, limited mostly by economic consideration but also by clinical applicability and specific adverse effects, is described for polyenes, 5 fluorocytosine, azoles, echinocandins and terbinafine. In the second part, current knowledge and experience in the treatment of selected fungal infections are overviewed. These mycoses include disseminated mold infections in small animals (dogs and cats) and avian species, upper respiratory tract infections of small animals (sino-nasal and sino-orbital aspergillosis) and horses (guttural pouch mycosis), eumycetoma, infections caused by dimorphic fungi, (blastomycosis, histoplasmosis, coccidioidomycosis, paracoccidioidomycosis and sporothrichosis) and by yeasts and yeast-like microorganism ( spp. and ).
本综述聚焦于兽医学特有的抗真菌治疗方面。第一部分描述了多烯类、5-氟胞嘧啶、唑类、棘白菌素类和特比萘芬的药物可及性,其主要受经济因素限制,但也受临床适用性和特定不良反应的限制。第二部分概述了目前在治疗某些真菌感染方面的知识和经验。这些真菌病包括小动物(犬和猫)及禽类的播散性霉菌感染、小动物(鼻旁窦和鼻眶曲霉病)和马(咽鼓管囊真菌病)的上呼吸道感染、足菌肿、由双相真菌(芽生菌病、组织胞浆菌病、球孢子菌病、副球孢子菌病和孢子丝菌病)以及酵母和酵母样微生物(属和种)引起的感染。