a Department of Cardiology and Internal Medicine, Military Institute of Medicine , Warsaw , Poland.
Clin Exp Hypertens. 2019;41(7):599-606. doi: 10.1080/10641963.2018.1523917. Epub 2018 Oct 31.
: Arterial hypertension (AH) can lead to the development of heart failure. : Evaluating the relationship between parameters of exercise capacity assessed via a six-minute walk test (6MWT) and cardiopulmonary exercise test (CPET), with a hemodynamic assessment via impedance cardiography (ICG), in patients with AH. : Exercise capacity was assessed in 98 hypertensive patients (54.5 ± 8.2 years) by means of oxygen uptake (VO) get from CPET, 6MWT distance (6MWTd) and hemodynamic parameters measured by ICG: heart rate (HR), stroke volume (SV), cardiac output (CO). Correlations between these parameters at rest, at anaerobic threshold (AT) and at peak of exercise as well as their changes (Δpeak-rest, Δpeak-AT, ΔAT-rest) were evaulated. : A large proportion of patients exhibited reduced exercise capacity, with 45.9% not reaching 80% of predicted peak VO and 43.9% not reaching predicted 6MWTd. Clinically relevant correlations were noted between the absolute peak values and AT values of VO vs HR and VO vs CO. Furthermore ΔVO(peak-AT) correlated with ΔHR(peak-AT), ΔCO(peak-AT) and ΔSV(peak-AT); ΔVO(peak-rest) with ΔHR(peak-rest) and ΔCO(peak-rest); ΔVO(AT-rest) with ΔHR(AT-rest) and ΔCO(AT-rest). Stronger correlations between changes in the evaluated parameters were demonstrated in the subgroup of subjects with peak VO < 80% of the predicted value; particularly ΔVO(peak-AT) correlated with ΔSV(peak-AT) and ΔCO(peak-AT). : The hemodynamic parameters show significant correlations with more measures of cardiovascular capacity of proven clinical utility. Impedance cardiography is a reliable method for assessing the cardiovascular response to exercise.
: 动脉高血压（AH）可导致心力衰竭的发展。 : 评估通过六分钟步行测试（6MWT）评估的运动能力参数与通过阻抗心动图（ICG）进行的心肺运动测试（CPET）之间的关系，并评估通过 ICG 评估的血流动力学参数。 : 在 98 名高血压患者（54.5±8.2 岁）中通过 CPET 中的摄氧量（VO），6MWT 距离（6MWTd）和 ICG 测量的血流动力学参数评估运动能力：心率（HR），心搏量（SV），心输出量（CO）。评估这些参数在休息时，在无氧阈（AT）时和在运动峰值时的相关性以及它们的变化（Δpeak-rest，Δpeak-AT，ΔAT-rest）。 : 很大一部分患者的运动能力下降，其中 45.9％未达到预测峰值 VO 的 80％，43.9％未达到预测的 6MWTd。在 VO 与 HR 和 VO 与 CO 的绝对值峰值和 AT 值之间观察到临床相关的相关性。此外，Δ VO（peak-AT）与Δ HR（peak-AT），Δ CO（peak-AT）和Δ SV（peak-AT）相关；Δ VO（peak-rest）与Δ HR（peak-rest）和Δ CO（peak-rest）相关；Δ VO（AT-rest）与Δ HR（AT-rest）和Δ CO（AT-rest）相关。在 VO 峰值<80％的预测值的亚组中，评估参数的变化之间显示出更强的相关性；特别是Δ VO（peak-AT）与Δ SV（peak-AT）和Δ CO（peak-AT）相关。 : 血流动力学参数与具有已证实临床实用性的更多心血管能力测量值具有显著相关性。阻抗心动图是评估运动心血管反应的可靠方法。
