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先前患有恶性肿瘤的患者中的原发性肺癌:一项全国性研究。

Primary lung cancer in patients with previous malignancies: a nationwide study.

机构信息

Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands.

Department of Radiology, Meander Medical Center, Amersfoort, The Netherlands.

出版信息

Thorax. 2019 May;74(5):492-495. doi: 10.1136/thoraxjnl-2018-211891. Epub 2018 Nov 1.

DOI:10.1136/thoraxjnl-2018-211891
PMID:30385691
Abstract

Overall survival of patients with cancer continues to increase and so they receive more frequent CT imaging, making oncological patients a growing population that effectively receives lung cancer screening in the course of daily practice. However, it is currently uncertain how early lung cancer detection in this subgroup of patients should be optimally managed. We describe the relationship between primary lung cancer and prior malignancies in a nationwide cohort, in an attempt to identify possible areas of improvement in nodule management. We found that a substantial number of subjects with lung cancer suffered from a prior malignancy; however, with the exception of otorhinolaryngeal malignancies, they did not show a high absolute risk for lung cancer. Future research should provide more data on how to handle this subgroup of patients in clinical and screening setting.

摘要

癌症患者的总体存活率持续上升,因此他们接受了更频繁的 CT 成像,使肿瘤患者成为在日常实践中接受肺癌筛查的人群不断增加。然而,目前尚不清楚如何优化该亚组患者的早期肺癌检测。我们在全国性队列中描述了原发性肺癌与先前恶性肿瘤之间的关系,试图确定在结节管理方面可能改进的领域。我们发现,相当数量的肺癌患者患有先前的恶性肿瘤;然而,除了耳鼻喉恶性肿瘤外,他们的肺癌绝对风险并不高。未来的研究应该提供更多关于如何在临床和筛查环境中处理这一组患者的数据。

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