Jha Anamika
Department of Radiology & Imaging, Institute of Medicine, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal.
JNMA J Nepal Med Assoc. 2018 Jul-Aug;56(212):787-790. doi: 10.31729/jnma.3536.
Elastrography used in addition to grey scale sonography increases its specificity. Elasticity contrast index (ECI) is based on strain elastrography and being a quantitative parameter, maybe more easy to obtain and reproducible while researches has been done in ECI in thyroid lesions, this is the first study, to the best of our knowledge to evaluate in breast lesions. This study was done to evaluate the diagnostic accuracy of Elasticity Contrast Index (ECI) in differentiating benign from malignant lesions of breast and to determine its cutoff value.
This is a descriptive cross-sectional study done at tertiary health care centre, which involved retrospective evaluation of data collected from September 2016 to March 2017. Conventional sonography was done followed by elastography on commercially available ultrasound machine. ECI was calculated in thyroid protocol available in the unit. Histopathological diagnosis was obtained for all the lesions and taken as gold standard.
A total of 89 breast lumps were evaluated, of which was 61 (69.3%) were benign and 27 (30.7%) malignant on histopathology. Independent t test revealed the average ECI value of benign lesions was 2.48 and malignant 5.1. Receiver operating curve showed ECI value of 3.25 as the cutoff, above which the lesions were malignant.
ECI is a quantitative elastography technique which can be easily used as an adjunct during breast sonography and can increase its specificity for diagnosing a lesion as malignant. This could reduce the number of false positive biopsies.
弹性成像与灰阶超声检查相结合可提高其特异性。弹性对比指数(ECI)基于应变弹性成像,作为一个定量参数,可能更容易获取且具有可重复性。虽然已有关于ECI在甲状腺病变中的研究,但据我们所知,这是第一项评估其在乳腺病变中的研究。本研究旨在评估弹性对比指数(ECI)在鉴别乳腺良恶性病变中的诊断准确性,并确定其临界值。
这是一项在三级医疗保健中心进行的描述性横断面研究,涉及对2016年9月至2017年3月收集的数据进行回顾性评估。先进行常规超声检查,然后在商用超声仪上进行弹性成像。在该设备可用的甲状腺检查方案中计算ECI。所有病变均获得组织病理学诊断,并将其作为金标准。
共评估了89个乳腺肿块,其中61个(69.3%)在组织病理学上为良性,27个(30.7%)为恶性。独立t检验显示,良性病变的平均ECI值为2.48,恶性病变为5.1。受试者操作曲线显示,ECI值为3.25作为临界值,高于该值的病变为恶性。
ECI是一种定量弹性成像技术,在乳腺超声检查中可轻松用作辅助手段,可提高其诊断病变为恶性的特异性。这可以减少假阳性活检的数量。