INTRODUCTION: Dental radiographs have always been the mainstay of the diagnosis of oral diseases. Even if the radiation hazard posed by the dental radiographs is low but still accumulation of such low level radiation in human body over a time period can pose a threat to the overall health of the individual. The aim of this study is to assess the knowledge of dental students about radiation protection and hazards. METHODS: The present cross sectional study was conducted by enrolling one hundred 4th year dental students from the two teaching hospitals in Chitwan district of Nepal. A questionnaire consisting of a total of 20 questions was distributed and each question was allocated 0.5 marks for correct response whereas no deduction for wrong answer. RESULTS: The results of the present study depicted that 85 (85%) of the total students enrolled in the study had "good" knowledge about the radiation physics, protection and hazards whereas only 15 (15%) of them had "poor" knowledge. CONCLUSIONS: The study concluded that teachers should involve in imparting more and more knowledge as well as training about the topic and dental curriculum should be altered so as to train the budding dentists about all aspects of radiation.