棕色脂肪中巨细胞病毒的存在。大鼠模型研究。
Presence of cytomegalovirus in brown fat. Study in a rat model.
作者信息
Bruggeman C A, Bruning J H, Grauls G, van den Bogaard A E, Bosman F
出版信息
Intervirology. 1987;27(1):32-7. doi: 10.1159/000149712.
PMID:3038776
Abstract
Cytomegalovirus infection of laboratory rats resulted in the appearance of virus and viral antigens in interscapular and periaortic brown fat. This appearance was limited to acute infection (first week post-infection) and was dependent on the route of inoculation. In our study virus could only be detected in subcutaneous brown fat in young rats (till 4 weeks of age), whereas in the deep brown fat (periaortic region) no age dependency was found.
摘要
实验大鼠的巨细胞病毒感染导致肩胛间和主动脉周围棕色脂肪中出现病毒和病毒抗原。这种现象仅限于急性感染（感染后第一周），并取决于接种途径。在我们的研究中，仅在幼鼠（直至4周龄）的皮下棕色脂肪中检测到病毒，而在深部棕色脂肪（主动脉周围区域）中未发现年龄依赖性。
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