使用常规剂量静脉注射吲哚菁绿进行近红外成像定位肺转移瘤：一项初步研究。
Near-Infrared Imaging Using Intravenous Indocyanine Green at a Conventional Dose to Locate Pulmonary Metastases: A Pilot Study.
作者信息
Hamaji Masatsugu, Chen-Yoshikawa Toyofumi Fengshi, Minami Manabu, Date Hiroshi
机构信息
Department of Thoracic Surgery, Kyoto University Hospital, Kyoto University, Sakyo-ku, Kyoto, Japan.
Department of Clinical Innovative Medicine, Kyoto University Hospital, Kyoto University, Sakyo-ku, Kyoto, Japan.
出版信息
Thorac Cardiovasc Surg. 2019 Dec;67(8):688-691. doi: 10.1055/s-0038-1675346. Epub 2018 Nov 2.
Intravenous indocyanine green (ICG) has been reported to localize intra-abdominal metastatic lesions in several clinical trials. Our pilot study aimed to investigate the feasibility and safety of ICG fluorescence localization in pulmonary metastasectomy using a near-infrared fluorescence thoracoscope. Each patient received intravenous 0.25 or 0.5 mg/kg of ICG. The maximum diameter of the tumor on computed tomography ranged from 0.5 to 3.5 (median: 1.15) cm. Intravenous ICG injection localized pulmonary metastases in a portion (3 patients) of the enrolled patients. Our preliminary results provided us with important information to modify the study protocol.
在多项临床试验中，静脉注射吲哚菁绿（ICG）已被报道可定位腹腔内转移病灶。我们的初步研究旨在探讨使用近红外荧光胸腔镜进行ICG荧光定位在肺转移瘤切除术中的可行性和安全性。每位患者静脉注射0.25或0.5 mg/kg的ICG。计算机断层扫描显示肿瘤的最大直径为0.5至3.5（中位数：1.15）厘米。静脉注射ICG使部分（3例）入组患者的肺转移灶得以定位。我们的初步结果为修改研究方案提供了重要信息。
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