全膝关节置换术后疼痛管理方案的比较:股神经阻滞与关节周围注射脂质体布比卡因联合收肌管阻滞
A Comparison of Pain Management Protocols Following Total Knee Arthroplasty: Femoral Nerve Block versus Periarticular Injection of Liposomal Bupivacaine with an Adductor Canal Block.
作者信息
Sandhu Sumeet, Zadzilka Jayson D, Nageeb Emmanuel, Siqueira Marcelo, Klika Alison K, Molloy Robert M, Higuera Carlos A
机构信息
Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio.
出版信息
Surg Technol Int. 2019 May 15;34:403-408.
BACKGROUND
Total knee arthroplasty (TKA) results in significant postoperative pain and a demanding postoperative path for recovery. This study was conducted to determine whether a femoral nerve block (FNB) or a periarticular injection of liposomal bupivacaine with an adductor canal block (LB+ACB) is superior for pain management.
MATERIALS AND METHODS
A total of 557 consecutive primary TKA cases performed at a single hospital between 2010-2014 were retrospectively reviewed. After enrollment criteria were met, 390 cases remained (FNB=181, LB+ACB=209). Inpatient and post-discharge variables related to pain, narcotic use, healthcare resource utilization, and cost were compared.
RESULTS
There were no significant differences in demographics between the two groups. There was also no significant difference in inpatient postoperative pain between the two groups. The FNB group consumed fewer narcotics overall compared to the LB+ACB group (p<0.001). However, the LB+ACB group experienced fewer opioid-related adverse events (p<0.001). The LB+ACB group had a shorter length of stay (p<.001), fewer readmissions (p=0.017) and reoperations (p=0.025), and lower costs (p<0.001).
DISCUSSION
LB+ACB proved to be an equally effective postoperative TKA pain management tool compared to FNB while displaying superiority in other increasingly important areas such as length of stay and cost. The larger amount of narcotic consumption is a concern, however, and there may be a small population of patients for whom LB+ACB is not the best option.
背景
全膝关节置换术(TKA)术后会导致显著疼痛,术后恢复过程也颇具挑战性。本研究旨在确定股神经阻滞(FNB)或关节周围注射脂质体布比卡因联合收肌管阻滞(LB+ACB)在疼痛管理方面是否更具优势。
材料与方法
回顾性分析了2010年至2014年间在一家医院连续进行的557例初次TKA病例。符合纳入标准后,剩余390例(FNB组=181例,LB+ACB组=209例)。比较了与疼痛、麻醉药物使用、医疗资源利用和成本相关的住院及出院后变量。
结果
两组患者的人口统计学特征无显著差异。两组患者术后住院期间的疼痛程度也无显著差异。与LB+ACB组相比,FNB组总体麻醉药物消耗量更少(p<0.001)。然而,LB+ACB组发生的阿片类药物相关不良事件较少(p<0.001)。LB+ACB组住院时间更短(p<0.001),再入院率更低(p=0.017),再次手术率更低(p=0.025),成本也更低(p<0.001)。
讨论
与FNB相比,LB+ACB被证明是一种同样有效的TKA术后疼痛管理工具,同时在住院时间和成本等其他日益重要的方面表现出优势。然而,麻醉药物消耗量较大是一个问题,可能有一小部分患者LB+ACB并非最佳选择。