Orr Patty, Shank Bettina Cobb, Hickson Shondell, Cooke Jennifer
School of Nursing, Austin Peay State University, PO Box 4658, Clarksville, TN 37044, USA.
School of Nursing, Austin Peay State University, PO Box 4658, Clarksville, TN 37044, USA.
Nurs Clin North Am. 2018 Dec;53(4):551-567. doi: 10.1016/j.cnur.2018.07.006. Epub 2018 Oct 11.
Progressive glomerular damage can occur as a result of various etiologic factors including infections, medications, diseases, and autoimmune disorders. This article discusses the clinical management of the leading conditions associated with glomerular disease, including glomerulosclerosis, diabetic nephropathy, focal segmental glomerulosclerosis, and membranous nephropathy. Glomerular damage and disease progression may lead to end stage renal disease. Clinical management is individualized, as based on causative factors and clinical manifestations, with the overall goal of limiting glomerular damage. Collaborative and comprehensive care is imperative to improving patient outcomes.
各种病因，包括感染、药物、疾病和自身免疫性疾病，都可能导致进行性肾小球损伤。本文讨论了与肾小球疾病相关的主要病症的临床管理，包括肾小球硬化症、糖尿病肾病、局灶节段性肾小球硬化症和膜性肾病。肾小球损伤和疾病进展可能导致终末期肾病。临床管理是个体化的，基于病因和临床表现，总体目标是限制肾小球损伤。协作和全面的护理对于改善患者预后至关重要。
