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一株携带 bla 和 mcr-1.5 基因的多重耐药柠檬酸杆菌临床分离株的特性。

Characterization of a multidrug resistant Citrobacter amalonaticus clinical isolate harboring bla and mcr-1.5 genes.

机构信息

Servicio Antimicrobianos, National and Regional Reference Laboratory in Antimicrobial Resistance, Instituto Nacional de Enfermedades Infecciosas (INEI)-ANLIS "Dr. C. Malbrán", Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.

Servicio Antimicrobianos, National and Regional Reference Laboratory in Antimicrobial Resistance, Instituto Nacional de Enfermedades Infecciosas (INEI)-ANLIS "Dr. C. Malbrán", Argentina.

出版信息

Infect Genet Evol. 2019 Jan;67:51-54. doi: 10.1016/j.meegid.2018.10.020. Epub 2018 Oct 31.

Abstract

A multidrug resistant isolate, identified as Citrobacter amalonaticus using MALDI-TOF MS and confirmed by genomic analysis, was recovered from a pediatric patient in a hospital from Buenos Aires, Argentina. By whole-genome sequencing a total of 16 resistance genes were detected, including bla and mcr-1.5. To the best of our knowledge this is the first description of these two genes together in a clinical isolate of the Citrobacter genus.

摘要

一株多药耐药分离株,通过 MALDI-TOF MS 鉴定为柠檬酸杆菌属,并通过基因组分析确认,从阿根廷布宜诺斯艾利斯一家医院的儿科患者中分离得到。通过全基因组测序共检测到 16 个耐药基因,包括 bla 和 mcr-1.5。据我们所知,这是这两个基因在柠檬酸杆菌属临床分离株中首次同时被描述。

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