相似文献
1
Single-Cell RNA Sequencing of Blood and Ileal T Cells From Patients With Crohn's Disease Reveals Tissue-Specific Characteristics and Drug Targets.
Gastroenterology. 2019 Feb;156(3):812-815.e22. doi: 10.1053/j.gastro.2018.10.046. Epub 2018 Nov 2.
2
T-cell Composition in Ileal and Colonic Creeping Fat - Separating Ileal from Colonic Crohn's Disease.
J Crohns Colitis. 2019 Jan 1;13(1):79-91. doi: 10.1093/ecco-jcc/jjy146.
3
Colonic epithelial miR-31 associates with the development of Crohn's phenotypes.
JCI Insight. 2018 Oct 4;3(19):122788. doi: 10.1172/jci.insight.122788.
4
Profoundly Expanded T-cell Clones in the Inflamed and Uninflamed Intestine of Patients With Crohn's Disease.
J Crohns Colitis. 2017 Jul 1;11(7):831-839. doi: 10.1093/ecco-jcc/jjx012.
5
Culture independent analysis of ileal mucosa reveals a selective increase in invasive Escherichia coli of novel phylogeny relative to depletion of Clostridiales in Crohn's disease involving the ileum.
ISME J. 2007 Sep;1(5):403-18. doi: 10.1038/ismej.2007.52. Epub 2007 Jul 12.
6
Characterization of T-cell Receptor Repertoire in Inflamed Tissues of Patients with Crohn's Disease Through Deep Sequencing.
Inflamm Bowel Dis. 2016 Jun;22(6):1275-85. doi: 10.1097/MIB.0000000000000752.
7
Mucosal healing of ileal lesions is associated with long-term clinical remission after infliximab maintenance treatment in patients with Crohn's disease.
Dig Endosc. 2015 Jan;27(1):73-81. doi: 10.1111/den.12313. Epub 2014 Jul 17.
8
An ileal Crohn's disease gene signature based on whole human genome expression profiles of disease unaffected ileal mucosal biopsies.
PLoS One. 2012;7(5):e37139. doi: 10.1371/journal.pone.0037139. Epub 2012 May 14.
9
Glucocorticoid treatment in ileal Crohn's disease: relief of symptoms but not of endoscopically viewed inflammation.
Gut. 1990 Mar;31(3):325-8. doi: 10.1136/gut.31.3.325.
10
CD28+ intraepithelial lymphocytes with long telomeres are recruited within the inflamed ileal mucosa in Crohn disease.
Hum Immunol. 2001 Jul;62(7):694-700. doi: 10.1016/s0198-8859(01)00258-0.
引用本文的文献
1
LAG3 limits regulatory T cell proliferation in α-synuclein gut-to-brain transmission model.
J Neuroinflammation. 2025 Jul 5;22(1):174. doi: 10.1186/s12974-025-03502-7.
2
Identification and multimodal characterization of a specialized epithelial cell type associated with Crohn's disease.
Nat Commun. 2024 Aug 22;15(1):7204. doi: 10.1038/s41467-024-51580-7.
3
Single cell transcriptomic analysis of the canine duodenum in chronic inflammatory enteropathy and health.
Front Immunol. 2024 Jun 12;15:1397590. doi: 10.3389/fimmu.2024.1397590. eCollection 2024.
4
Identification of master regulator genes controlling pathogenic CD4 T cell fate in inflammatory bowel disease through transcriptional network analysis.
Sci Rep. 2024 May 8;14(1):10553. doi: 10.1038/s41598-024-61158-4.
5
Single-cell transcriptomics reveals activation of endothelial cell and identifies LHPP as a potential target in ulcerative colitis.
Heliyon. 2024 Apr 3;10(7):e29163. doi: 10.1016/j.heliyon.2024.e29163. eCollection 2024 Apr 15.
6
Single-cell analysis identifies phospholysine phosphohistidine inorganic pyrophosphate phosphatase as a target in ulcerative colitis.
World J Gastroenterol. 2023 Dec 28;29(48):6222-6234. doi: 10.3748/wjg.v29.i48.6222.
7
Deciphering the different phases of preclinical inflammatory bowel disease.
Nat Rev Gastroenterol Hepatol. 2024 Feb;21(2):86-100. doi: 10.1038/s41575-023-00854-4. Epub 2023 Nov 10.
8
A Specialized Epithelial Cell Type Regulating Mucosal Immunity and Driving Human Crohn's Disease.
bioRxiv. 2023 Oct 2:2023.09.30.560293. doi: 10.1101/2023.09.30.560293.
9
A Roadmap for the Human Gut Cell Atlas.
Nat Rev Gastroenterol Hepatol. 2023 Sep;20(9):597-614. doi: 10.1038/s41575-023-00784-1. Epub 2023 May 31.
10
The single-cell transcriptional landscape of innate and adaptive lymphocytes in pediatric-onset colitis.
Cell Rep Med. 2023 May 16;4(5):101038. doi: 10.1016/j.xcrm.2023.101038. Epub 2023 May 8.
本文引用的文献
1
The Human Cell Atlas.
Elife. 2017 Dec 5;6:e27041. doi: 10.7554/eLife.27041.
2
Massively parallel digital transcriptional profiling of single cells.
Nat Commun. 2017 Jan 16;8:14049. doi: 10.1038/ncomms14049.
3
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.
Nat Genet. 2015 Sep;47(9):979-986. doi: 10.1038/ng.3359. Epub 2015 Jul 20.
4
Genetic and epigenetic fine mapping of causal autoimmune disease variants.
Nature. 2015 Feb 19;518(7539):337-43. doi: 10.1038/nature13835. Epub 2014 Oct 29.
5
Generation of primary human intestinal T cell transcriptomes reveals differential expression at genetic risk loci for immune-mediated disease.
Gut. 2015 Feb;64(2):250-9. doi: 10.1136/gutjnl-2013-306657. Epub 2014 May 5.
Zotero 插件