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法国药物警戒网络(FAN)对滥用/依赖病例的识别:法国南锡药物警戒中心和心理治疗中心的一项试点研究

[Identification of abuse/dependence cases by the French addictovigilance network (FAN): A pilot study of the addictovigilance center and the psychotherapeutic center of Nancy (France)].

作者信息

Barberot Pauline, Gibaja Valérie, Benkhedda Célia, Dobre Daniela, Tournebize Juliana, Kahn Jean-Pierre

机构信息

Centre d'évaluation et d'information sur la pharmacodépendance et addictovigilance (CEIP-A), CHRU de Nancy, hôpital central, 29, avenue du Maréchal de Lattre de Tassigny, 54035 Nancy, France.

Centre d'évaluation et d'information sur la pharmacodépendance et addictovigilance (CEIP-A), CHRU de Nancy, hôpital central, 29, avenue du Maréchal de Lattre de Tassigny, 54035 Nancy, France; French Addictovigilance Network (FAN), 54035 Nancy, France.

出版信息

Therapie. 2019 Jun;74(3):389-397. doi: 10.1016/j.therap.2018.10.002. Epub 2018 Oct 13.

Abstract

OBJECTIVES

France is the only European country with a dedicated addictovigilance network (French addictovigilance network [FAN]). However, the reporting of cases of abuse/dependence is insufficient. In an attempt to overcome this under-reporting, data from the medical information systems program (PMSI) is regularly used to identify cases. Since addictions are frequently associated with psychiatric comorbidities, a pilot study was conducted for the first time in a psychiatric hospital. It aims, through a PMSI request, to identify the sociodemographic characteristics and psychiatric diagnoses of patients consuming psychoactive substances (PAS) and the PAS types consumed.

METHODS

This is a retrospective observational study conducted over a nine-month period at the psychotherapeutic center of Nancy (CPN). The codes used for the PMSI request are those of the international classification of diseases, tenth revision (ICD-10), codes F10 to F19 that characterize mental and behavioral disorders associated with the use of PAS. Cases presenting the four criteria necessary for an addictovigilance notification: (1) identified notifier, (2) identified patient, (3) known consumed product (s) and (4) presence of an effect related to the abuse/dependence of PAS; were retained and analyzed.

RESULTS

On an initial number of 252 cases, 82 cases of abuse/dependence were retained. The selected sample is predominantly male (67%). Cannabis (29%) and heroin (15%) are the most common illicit PAS. Regarding drugs, the consumption of benzodiazepines, a predominantly female phenomenon, is observed in 34% of subjects. Sixty-four per cent of the subjects were diagnosed "disorders related to the use of PAS", 14% as neurotic disorders, 9% as schizophrenia and 5% as of the mood disorders.

CONCLUSION

This study identified a significant number of potentially reportable cases to the French Addictovigilance Network and demonstrated the interest of investigating cases of abuse/dependence in a psychiatric hospital.

摘要

目的

法国是欧洲唯一拥有专门药物警戒网络(法国药物警戒网络[FAN])的国家。然而,滥用/依赖病例的报告并不充分。为了克服这种报告不足的情况,医学信息系统计划(PMSI)的数据被定期用于识别病例。由于成瘾常常与精神疾病共病相关,因此首次在一家精神病医院进行了一项试点研究。其目的是通过PMSI请求,识别使用精神活性物质(PAS)的患者的社会人口统计学特征和精神诊断以及所使用的PAS类型。

方法

这是一项在南锡心理治疗中心(CPN)进行的为期九个月的回顾性观察研究。PMSI请求所使用的编码是国际疾病分类第十版(ICD - 10)中F10至F19的编码,这些编码用于描述与使用PAS相关的精神和行为障碍。呈现药物警戒通报所需的四个标准的病例:(1)已识别的通报者,(2)已识别的患者,(3)已知使用的产品,以及(4)存在与PAS滥用/依赖相关的效应;被保留并进行分析。

结果

在最初的252例病例中,保留了82例滥用/依赖病例。所选样本以男性为主(67%)。大麻(29%)和海洛因(15%)是最常见的非法PAS。在药物方面,34%的受试者存在苯二氮䓬类药物的使用情况,这一现象以女性为主。64%的受试者被诊断为“与使用PAS相关的障碍”,14%为神经症性障碍,9%为精神分裂症,5%为心境障碍。

结论

本研究识别出大量可能需向法国药物警戒网络报告的病例,并证明了在精神病医院调查滥用/依赖病例的意义。

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