Jouanjus Emilie, Gibaja Valérie, Kahn Jean-Pierre, Haramburu Françoise, Daveluy Amélie
Centre d'Addictovigilance, Service de Pharmacologie Médicale et Clinique, CHU, Faculté de Médecine, Toulouse, France.
Centre d'Addictovigilance, Hôpital Central, CHU de Nancy, Nancy, France.
Therapie. 2015 Mar-Apr;70(2):113-31. doi: 10.2515/therapie/2015011. Epub 2015 Apr 9.
The French addictovigilance network (addictovigilance: surveillance of addiction), composed of 13 Addictovigilance Centres, was set up in 1990 in order to achieve reliable surveillance and evaluation of abuse and dependence cases due to psychoactive substances (alcohol and tobacco excepted). The detection of safety signals is one of the roles of the addictovigilance centres. Signals from spontaneous reports need to be analyzed before further communication. In addictovigilance, signals may be linked to adverse effects (deaths, pathological signs), to products (new psychoactive substances with potentially dangerous effects) or to practices (new administration routes, new contexts of use). These signals are provided by numerous partners among whom the addictovigilance network has to raise awareness about information that may possibly be an alert signal. The watchful attitude of all partners will make it possible that signals will be, after analyze, considered as true alerts. The addictovigilance network collects data, assess the potential for addiction of psychoactive drugs to provide information on the risk of addiction and give opinions for public health decisions (harm reduction or prevention programs, psychoactive substances control, health alerts).
法国药物警戒网络（药物警戒：成瘾监测）由13个药物警戒中心组成，于1990年设立，旨在对除酒精和烟草外的精神活性物质所致的滥用和依赖病例进行可靠的监测和评估。发现安全信号是药物警戒中心的职责之一。来自自发报告的信号在进一步通报之前需要进行分析。在药物警戒中，信号可能与不良反应（死亡、病理体征）、产品（具有潜在危险作用的新型精神活性物质）或做法（新的给药途径、新的使用环境）有关。这些信号由众多合作伙伴提供，药物警戒网络必须提高这些合作伙伴对可能构成警报信号的信息的认识。所有合作伙伴保持警惕的态度将使信号在分析后有可能被视为真正的警报。药物警戒网络收集数据，评估精神活性药物的成瘾潜力，以提供有关成瘾风险的信息，并为公共卫生决策（减少伤害或预防计划、精神活性物质管制、健康警报）提供意见。
