Santillan Alejandro, Knopman Jared, Patsalides Athos, Pierre Gobin Y
Division of Interventional Neuroradiology, New York Presbyterian Hospital/Weill Cornell Medical Center, New York, USA.
Interv Neuroradiol. 2019 Apr;25(2):177-181. doi: 10.1177/1591019918808026. Epub 2018 Nov 4.
Myxomas are slowly growing benign neoplasms and represent the most common tumor of the heart. Embolism from cardiac myxoma occurs in 30-45% of patients and in at least half of the cases cerebral arteries are affected leading mainly to embolic ischemic strokes and rarely to delayed intracranial aneurysm formation. We present two cases with delayed intracranial aneurysmal formation 14 years and 18 years after cardiac myxoma resection. To the best of our knowledge these two cases represent the longest time interval between aneurysm detection after complete cardiac myxoma resection with no recurrence confirmed by transesophageal echocardiogram. Our study also provides the longest clinical and radiological follow-up on this type of lesion.
黏液瘤是生长缓慢的良性肿瘤，是心脏最常见的肿瘤。心脏黏液瘤栓塞发生在30% - 45%的患者中，至少一半的病例脑动脉受到影响，主要导致栓塞性缺血性中风，很少导致延迟性颅内动脉瘤形成。我们报告两例在心脏黏液瘤切除术后14年和18年出现延迟性颅内动脉瘤形成的病例。据我们所知，这两例代表了经食管超声心动图证实心脏黏液瘤完全切除后至动脉瘤发现之间最长的时间间隔，且无复发。我们的研究还提供了对这类病变最长的临床和影像学随访。
