Teskey G C, Ossenkopp K P, Prato F S, Sestini E
Physiol Chem Phys Med NMR. 1987;19(1):43-9.
The effect of exposure to the magnetic and radio-frequency fields associated with Nuclear Magnetic Resonance Imaging (MRI) on survivability and long-term stress reactivity levels was examined in male rats. Rats in the experimental condition were exposed to MRI for 22.5 minutes for five successive days (Expt. 1) or 23.3 minutes for twenty-one successive days (Expt. 2). Sham field exposed animals received the identical treatment as the exposed animals except that the magnetic and radio-frequency fields were absent. Control rats were also maintained. Thirteen to twenty-two months after the exposure procedure the remaining rats were sacrificed and their whole body, spleen, heart, thymus, and adrenal weights were recorded. Blood samples were taken for measurements of red and white blood cell counts, hemoglobin content, as well as adrenocorticotrophin and corticosterone levels. The results fail to provide any evidence for changes in survivability and long-term stress reactivity levels in rats exposed to MRI and thus give no grounds to challenge the view that MRI is a safe diagnostic procedure.
研究了雄性大鼠暴露于与核磁共振成像（MRI）相关的磁场和射频场对其生存能力和长期应激反应水平的影响。实验条件下的大鼠连续五天每天暴露于MRI环境22.5分钟（实验1）或连续二十一天每天暴露23.3分钟（实验2）。假暴露组动物接受与暴露组动物相同的处理，只是不存在磁场和射频场。同时也设置了对照大鼠。暴露程序结束后的13至22个月，处死剩余大鼠并记录其全身、脾脏、心脏、胸腺和肾上腺的重量。采集血样以测量红细胞和白细胞计数、血红蛋白含量以及促肾上腺皮质激素和皮质酮水平。结果未能提供任何证据表明暴露于MRI的大鼠在生存能力和长期应激反应水平上有变化，因此没有理由质疑MRI是一种安全诊断程序的观点。
