Suppr超能文献

骨盆骨折致血流动力学不稳定患者行腹膜外盆腔填塞的效果及术后伤口感染。

Effectiveness and postoperative wound infection of preperitoneal pelvic packing in patients with hemodynamic instability caused by pelvic fracture.

机构信息

Trauma Center, Wonju Severance Christian Hospital, Wonju, Korea.

Department of Surgery, Yonsei University Wonju College of Medicine, Wonju, Korea.

出版信息

PLoS One. 2018 Nov 5;13(11):e0206991. doi: 10.1371/journal.pone.0206991. eCollection 2018.

Abstract

INTRODUCTION

Despite the use of a multidisciplinary treatment approach, the mortality rate of hemodynamic instability due to severe pelvic fracture remains 40-60%. Several recent studies have shown that preperitoneal pelvic packing (PPP) was useful for achieving hemostasis in these patients in the acute phase. However, few studies have examined postoperative complications. The purpose of the present study was to evaluate clinical outcomes and wound infections of PPP in these patients.

MATERIALS AND METHODS

We retrospectively reviewed the medical charts of 62 patients with hemorrhagic shock due to pelvic fracture between March 2011 and May 2017. Excluding four patients (two with other major hemorrhage sites and two who experienced cardiac arrest in the emergency room), the patients were divided into PPP (n = 30) and non-PPP (n = 28) groups according to PPP application. Clinical outcomes including early-stage mortality, transfusion amount, and surgical site infection (SSI) were compared between the two groups.

RESULTS

The overall mortality rate was 48.3% and the mean Injury Severity Score (ISS) was 39 ± 9. The 30 patients in the PPP group had a significantly lower hemorrhage-induced mortality rate than the 28 patients in the non-PPP group (16.7% vs 50%, p = 0.019), although both groups had similar patient characteristics (age, ISS, and initial serum lactate level). Independent factors associated with hemorrhage-induced mortality were PPP and the requirement of packed red blood cells for 4 h. In the PPP group, SSI occurred in 5 of 25 (20%) patients.

CONCLUSIONS

PPP may be considered as a hemostatic modality for hemodynamic instability due to pelvic fracture because it reduces the hemorrhage-induced mortality rate. However, wound infections after the procedure should be considered.

摘要

简介

尽管采用了多学科治疗方法,因严重骨盆骨折导致血流动力学不稳定的死亡率仍为 40-60%。最近的几项研究表明,腹膜前骨盆填塞(PPP)在急性阶段对这些患者实现止血是有用的。然而,很少有研究检查术后并发症。本研究的目的是评估这些患者 PPP 的临床结果和伤口感染。

材料和方法

我们回顾性分析了 2011 年 3 月至 2017 年 5 月因骨盆骨折合并出血性休克的 62 例患者的病历。排除 4 例(其中 2 例有其他主要出血部位,2 例在急诊室发生心脏骤停)患者后,根据 PPP 应用情况将患者分为 PPP(n=30)和非-PPP(n=28)组。比较两组患者的早期死亡率、输血量和手术部位感染(SSI)等临床结果。

结果

总死亡率为 48.3%,损伤严重程度评分(ISS)平均值为 39±9。PPP 组 30 例患者的出血性死亡率明显低于非-PPP 组 28 例患者(16.7%比 50%,p=0.019),尽管两组患者的特征(年龄、ISS 和初始血清乳酸水平)相似。与出血性死亡率相关的独立因素是 PPP 和 4 小时内需要浓缩红细胞。在 PPP 组,25 例中有 5 例(20%)发生 SSI。

结论

PPP 可被视为骨盆骨折导致血流动力学不稳定的止血方法,因为它降低了出血性死亡率。然而,应考虑术后伤口感染。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验