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男性患者小腿象皮肿并发血管肉瘤:一种罕见的临床并发症、病例报告及文献综述

Angiosarcoma complicating lower leg elephantiasis in a male patient: An unusual clinical complication, case report and literature review.

作者信息

Shavit Eran, Alavi Afsaneh, Limacher James J, Sibbald R Gary

机构信息

Division of Dermatology, Department of Medicine, Women's College Hospital, University of Toronto, Toronto, ON, Canada.

出版信息

SAGE Open Med Case Rep. 2018 Oct 30;6:2050313X18796343. doi: 10.1177/2050313X18796343. eCollection 2018.

DOI:10.1177/2050313X18796343
PMID:30397474
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6207953/
Abstract

Chronic lymphedema is rarely complicated by an angiosarcoma. Angiosarcoma superimposed on chronic lymphedema (Stewart-Treves syndrome) is usually seen post breast cancer surgery accompanied by lymph node resection of the axilla. This is a case report of a 59-year-old male patient with elephantiasis that developed an angiosarcoma of the lower leg. He died a month after the diagnostic biopsy was obtained. This is a rare multifocal tumor in a male with an unusual lower leg location. We reviewed the literature and the need to differentiate this often deadly lesion from a Kaposi's sarcoma.

摘要

慢性淋巴水肿很少并发血管肉瘤。叠加在慢性淋巴水肿上的血管肉瘤(斯图尔特-特里夫斯综合征)通常见于乳腺癌手术后伴有腋窝淋巴结切除的患者。本文报告一例59岁男性患者,患有象皮肿,并发小腿血管肉瘤。在获得诊断性活检一个月后患者死亡。这是一例罕见的多灶性肿瘤,发生在男性患者的小腿这一不寻常部位。我们回顾了文献,并强调需要将这种往往致命的病变与卡波西肉瘤相鉴别。

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Angiosarcoma complicating lower leg elephantiasis in a male patient: An unusual clinical complication, case report and literature review.男性患者小腿象皮肿并发血管肉瘤:一种罕见的临床并发症、病例报告及文献综述
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Angiosarcoma arising in massive localized lymphedema.

本文引用的文献

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Cutaneous angiosarcoma: a current update.皮肤血管肉瘤:最新进展
J Clin Pathol. 2017 Nov;70(11):917-925. doi: 10.1136/jclinpath-2017-204601. Epub 2017 Sep 15.
2
Stewart-Treves Syndrome: A Case Report and Review of the Literature.斯图尔特-特里夫斯综合征:一例报告及文献综述
Case Rep Oncol. 2016 Apr 1;9(1):205-11. doi: 10.1159/000445427. eCollection 2016 Jan-Apr.
3
Angiosarcoma (Stewart-Treves syndrome) in postmastectomy patients: report of 10 cases and review of literature.乳房切除术后患者的血管肉瘤(斯图尔特-特里夫斯综合征):10例报告及文献复习
发生于局限性淋巴水肿的血管肉瘤。
Skeletal Radiol. 2020 May;49(5):815-818. doi: 10.1007/s00256-020-03373-4. Epub 2020 Jan 16.
Int J Clin Exp Pathol. 2015 Sep 1;8(9):11108-15. eCollection 2015.
4
Lymphedema-related angiogenic tumors and other malignancies.淋巴水肿相关的血管生成性肿瘤及其他恶性肿瘤。
Clin Dermatol. 2014 Sep-Oct;32(5):616-20. doi: 10.1016/j.clindermatol.2014.04.008.
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Massive localized lymphedema, a disease unique to the morbidly obese: a case study.巨大局限性淋巴水肿——一种病态肥胖患者特有的疾病:病例报告
Ostomy Wound Manage. 2014 Jan;60(1):30-5.
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Clinical experience of stewart-treves syndrome in the lower leg.小腿部斯图尔特-特里夫斯综合征的临床经验
Arch Plast Surg. 2013 May;40(3):275-7. doi: 10.5999/aps.2013.40.3.275. Epub 2013 May 16.
7
Stewart-Treves syndrome angiosarcoma expresses phenotypes of both blood and lymphatic capillaries.Stewart-Treves 综合征血管肉瘤表达血液和淋巴管毛细血管的表型。
Chin Med J (Engl). 2013 Jan;126(2):231-7.
8
A Stewart-Treves syndrome of the lower limb.下肢的斯图尔特-特里夫斯综合征。
Dermatol Online J. 2012 Jun 15;18(6):14.
9
Stewart-Treves syndrome: pathogenesis and management.Stewart-Treves 综合征:发病机制与治疗。
J Am Acad Dermatol. 2012 Dec;67(6):1342-8. doi: 10.1016/j.jaad.2012.04.028. Epub 2012 Jun 8.
10
Stewart-Treves syndrome after cervical cancer.
Intern Med. 2012;51(5):513. doi: 10.2169/internalmedicine.51.7002. Epub 2012 Mar 1.