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双膦酸盐类药物诱发的非典型股骨转子下骨折:一例报告

Bisphosphonates-induced Atypical Subtrochanteric Fracture Femur: A Case Report.

作者信息

Yadav Siddhart, Khanna Vikram

机构信息

Orthopaedics, Apollo Hospital, Mumbai, IND.

Orthopaedics, Ranjana Hospital, Allahabad, IND.

出版信息

Cureus. 2018 Jul 6;10(7):e2937. doi: 10.7759/cureus.2937.

Abstract

A 71-year-old female came to our institute with a subtrochanteric left femur fracture following a fall from her bed. It was a low-energy trauma, and the X-rays were suggestive of an atypical fracture following bisphosphonate therapy for five years. The fracture was fixed with intramedullary nailing following which she was started on partial weight-bearing walking after three weeks. The fracture went on to a nonunion; after one year, the fracture site was opened and bone grafting with bone marrow injection, along with augmented plating, was done. The fracture showed signs of union three months postoperatively. Fractures associated with bisphosphonate therapy may be associated with delayed union or nonunion and should be explained to the patient.

摘要

一名71岁女性因从床上跌落导致左股骨转子下骨折前来我院就诊。这是一次低能量创伤,X线片提示为接受双膦酸盐治疗五年后的非典型骨折。骨折采用髓内钉固定,三周后开始部分负重行走。骨折出现不愈合;一年后,打开骨折部位,进行骨髓注射骨移植及增强钢板固定。术后三个月骨折显示出愈合迹象。与双膦酸盐治疗相关的骨折可能会出现延迟愈合或不愈合,应向患者解释清楚。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d417/6207284/f97f405ae893/cureus-0010-00000002937-i01.jpg

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