Synthesis of Proteins Encoded by the Early Genes E2, E6, and E7 of Papillomavirus of Type 16 in the Plant Expression System.

作者信息

Salyaev R K, Rekoslavskaya N I, Stolbikov A S

机构信息

Siberian Institute of Plant Physiology and Biochemistry, Siberian Branch, Russian Academy of Sciences, Irkutsk, 664033, Russia.

Irkutsk Scientific Center, Siberian Branch, Russian Academy of Sciences, Irkutsk, 664033, Russia.

出版信息

Dokl Biochem Biophys. 2018 Sep;482(1):271-274. doi: 10.1134/S1607672918050113. Epub 2018 Nov 5.

An expression system for the synthesis of early antigenic proteins HPV16 E2, HPV16 E6, and HPV16 E7 of high-risk papillomavirus based on transgenic tomato fruits was developed. It is planned to use the early antigenic proteins synthesized to create a therapeutic vaccine against cervical cancer.