Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, University of California Irvine, Orange, California.
Obstet Gynecol. 2018 Dec;132(6):1337-1345. doi: 10.1097/AOG.0000000000002968.
Sacral nerve stimulation delivers nonpainful electrical pulses to the sacral nerves that modulate the reflexes that control the bladder, bowels, and pelvic floor musculature. This relatively simple procedure was generated to improve and restore function in patients with a variety of pelvic floor disorders. Currently this therapy is approved for use in patients with urgency urinary incontinence, urinary urgency-frequency, nonobstructive urinary retention, and fecal incontinence. This review includes the history of this treatment modality, explains the mechanism of action, and describes the procedure for implantation of this device. Additionally, advancements in this treatment over the past two decades and landmark literature to date regarding sacral nerve stimulation are reviewed. Current literature regarding off-label uses of this treatment modality for a variety of pelvic floor disorders is also discussed.
骶神经刺激通过向骶神经传递无痛的电脉冲来调节控制膀胱、肠道和盆底肌肉的反射。这一相对简单的程序旨在改善和恢复各种盆底功能障碍患者的功能。目前,该疗法已获准用于治疗急迫性尿失禁、尿急-尿频、非梗阻性尿潴留和粪便失禁患者。本综述包括该治疗方式的历史,解释了其作用机制,并介绍了该装置植入的过程。此外,还回顾了过去 20 年来该治疗方法的进展以及关于骶神经刺激的重要文献。还讨论了目前关于该治疗方式在各种盆底功能障碍中的非适应证应用的文献。