Division of Gynecologic Oncology, Department of Surgery and Surgical Oncology, University Health Network, Princess Margaret Cancer Centre, the Department of Obstetrics and Gynecology, University of Toronto, and the Section of Pediatric Gynecology, Division of Endocrinology, the Division of Pediatric Urology, Department of Surgery, and the Division of Hematology/Oncology, Hospital for Sick Children, Toronto, Ontario, Canada.
Obstet Gynecol. 2018 Dec;132(6):1486-1490. doi: 10.1097/AOG.0000000000002949.
Embryonal rhabdomyosarcoma of the cervix is a rare and aggressive malignancy that usually affects children and young adults.
We describe a 2-year-old patient who presented with a mass protruding through the vaginal introitus. Preoperative investigations including vaginoscopy, hysteroscopy, magnetic resonance imaging, and biopsies confirmed embryonal rhabdomyosarcoma, botryoid subtype, arising from the cervix. She was successfully treated with neoadjuvant chemotherapy and interval laparoscopic radical trachelectomy to achieve remission.
Collaboration between the pediatric and adult surgical and medical oncology teams was critical to implement this fertility-sparing treatment strategy in such a young girl having this rare tumor.
宫颈胚胎性横纹肌肉瘤是一种罕见且侵袭性强的恶性肿瘤，通常发生于儿童和青年。
我们描述了一名 2 岁的患者，其阴道入口处有一个肿块突出。术前检查包括阴道镜、宫腔镜、磁共振成像和活检，均证实为源自宫颈的胚胎性横纹肌肉瘤，葡萄状亚型。她成功地接受了新辅助化疗和间隔腹腔镜根治性宫颈切除术以达到缓解。
儿科和成人外科及肿瘤内科团队之间的合作对于在如此年幼的女孩中实施这种保留生育能力的治疗策略至关重要，因为她患有这种罕见的肿瘤。
