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出院后腘动脉损伤修复的结果:一项大规模基于人群的分析。

Outcomes for popliteal artery injury repair after discharge: A large-scale population-based analysis.

机构信息

From the Trauma Service (W.J.B., R.Y.C., M.J.S., J.M.B., L.E.W., V.B., C.S.), Scripps Mercy Hospital, San Diego, California.

出版信息

J Trauma Acute Care Surg. 2019 Feb;86(2):173-180. doi: 10.1097/TA.0000000000002118.

Abstract

BACKGROUND

Although short-term outcomes for popliteal artery injury after endovascular versus open repair appear similar, studies on outcomes after discharge are limited. We evaluated popliteal artery injury repair in a population-based data set. We hypothesized that postdischarge outcomes for open repair are superior to endovascular repair.

METHODS

Patients with popliteal artery injury were identified in the California Office of Statewide Health Planning and Development 2007-2014 discharge database. Popliteal artery injury and other lower-extremity injuries were identified using International Classification of Diseases, Ninth Revision, Clinical Modification diagnosis codes. Procedure codes were evaluated to identify open repair, endovascular repair, fasciotomy, and amputation. Primary outcomes were mortality or amputation. The association between repair method and each outcome was evaluated with logistic regression. Postdischarge amputation and all-cause mortality were evaluated using survival analysis.

RESULTS

Among 769 patients with popliteal artery injury, open repair occurred in 456 (59.3%), endovascular repair in 37 (4.3%), combined endovascular and open in 18 (2.3%), and nonoperative management in 258 (33.6%). Fasciotomy was performed more frequently in open than endovascular repair (p = 0.001) during index admission. Amputation rate was also increased in open repair, but this was not significant (p = 0.196). Arterial thromboembolus during index admission was more likely after endovascular or combined endovascular and open compared with open (24.3%, 55.6%, 16.7%, respectively, p < 0.001). Patients requiring both endovascular and open were more likely to undergo amputation postdischarge (hazard ratio, 4.11; 95% confidence interval, 1.16-14.53). Patients undergoing endovascular repair were more likely to die postdischarge (hazard ratio, 4.43; 95% confidence interval, 1.06-18.56) compared with patients who had open repair (median, 98.5 days postdischarge).

CONCLUSIONS

In a large cohort with popliteal artery injury, open repair was associated with lower rates of index admission arterial thromboembolus as well as postdischarge amputation and all-cause mortality. We recommend conducting a prospective multicenter study to examine the appropriate use of endovascular repair for this injury.

LEVEL OF EVIDENCE

Therapeutic, level IV.

摘要

背景

虽然血管内修复与开放修复后腘动脉损伤的短期结果相似,但关于出院后结果的研究有限。我们在一个基于人群的数据集评估了腘动脉损伤修复。我们假设开放修复的出院后结果优于血管内修复。

方法

在加利福尼亚州全州卫生规划和发展局 2007-2014 年的出院数据库中确定了腘动脉损伤患者。使用国际疾病分类,第九版,临床修正诊断代码确定腘动脉损伤和其他下肢损伤。评估手术代码以确定开放修复、血管内修复、筋膜切开术和截肢。主要结果是死亡或截肢。使用逻辑回归评估修复方法与每种结果之间的关联。使用生存分析评估出院后截肢和全因死亡率。

结果

在 769 名患有腘动脉损伤的患者中,456 名(59.3%)接受了开放修复,37 名(4.3%)接受了血管内修复,18 名(2.3%)接受了血管内联合开放修复,258 名(33.6%)接受了非手术治疗。在指数入院期间,筋膜切开术在开放修复中比血管内修复更常见(p=0.001)。开放修复的截肢率也较高,但差异无统计学意义(p=0.196)。与开放修复相比,指数入院期间的动脉血栓栓塞在血管内或联合血管内和开放修复后更常见(分别为 24.3%、55.6%、16.7%,p<0.001)。需要血管内和开放修复的患者出院后更有可能截肢(风险比,4.11;95%置信区间,1.16-14.53)。与接受开放修复的患者相比,接受血管内修复的患者出院后更有可能死亡(风险比,4.43;95%置信区间,1.06-18.56)(中位时间,出院后 98.5 天)。

结论

在一个大型腘动脉损伤队列中,开放修复与指数入院时动脉血栓栓塞以及出院后截肢和全因死亡率较低相关。我们建议进行一项前瞻性多中心研究,以检查血管内修复这种损伤的适当使用。

证据水平

治疗,IV 级。

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