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大型创伤中心的开放性胫骨骨折:一项关于当前治疗情况的全国性前瞻性队列研究。

Open tibial fractures in major trauma centres: A national prospective cohort study of current practice.

作者信息

Young K, Aquilina A, Chesser T J S, Costa M L, Hettiaratchy S, Kelly M B, Moran C G, Pallister I, Woodford M

机构信息

Queen Victoria Hospital, East Grinstead, RH19 3DZ, UK.

Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, University of Oxford, Kadoorie Centre, John Radcliffe Hospital, Oxford, OX3 9DU, UK.

出版信息

Injury. 2019 Feb;50(2):497-502. doi: 10.1016/j.injury.2018.10.028. Epub 2018 Oct 29.

Abstract

AIMS

To assess current national practice in the management of severe open tibial fractures against national standards, using data collected by the Trauma and Audit Research Network.

MATERIALS AND METHODS

Demographic, injury-specific, and outcome data were obtained for all grade IIIB/C fractures admitted to Major Trauma Centres in England from October 2014 to January 2016.

RESULTS

Data was available for 646 patients with recorded grade IIIB/C fractures. The male to female ratio was 2.3:1, mean age 47 years. 77% received antibiotics within 3 h of admission, 82% were debrided within 24 h. Soft tissue coverage was achieved within 72 h of admission in 71%. The amputation rate was 8.7%. 4.3% of patients required further theatre visits for infection during the index admission. The timing of antibiotics and surgery could not be correlated with returns to theatre for early infection. There were significant differences in the management and outcomes of patients aged 65 and over, with an increase in mortality and amputation rates.

CONCLUSIONS

Good outcomes are reported from the management of IIIB/C fractures in Major Trauma Centres in England. Overall compliance with national standards is particularly poor in the elderly. Compliance did not appear to affect rates of returning to theatre or early infection. Appropriately applied patient reported outcome measures are needed to enhance the evidence-base for management of these injuries.

摘要

目的

利用创伤与审计研究网络收集的数据,对照国家标准评估当前国内严重开放性胫骨骨折的治疗情况。

材料与方法

获取2014年10月至2016年1月间收治于英格兰各大创伤中心的所有ⅢB/C级骨折患者的人口统计学、损伤特异性及预后数据。

结果

有646例记录为ⅢB/C级骨折的患者的数据。男女比例为2.3:1,平均年龄47岁。77%的患者在入院3小时内接受了抗生素治疗,82%的患者在24小时内进行了清创。71%的患者在入院72小时内实现了软组织覆盖。截肢率为8.7%。4.3%的患者在首次住院期间因感染需要再次手术。抗生素使用时间和手术时间与因早期感染再次手术无关。65岁及以上患者的治疗和预后存在显著差异,死亡率和截肢率有所增加。

结论

英格兰各大创伤中心对ⅢB/C级骨折的治疗取得了良好的效果。总体而言,老年人对国家标准的依从性特别差。依从性似乎并未影响再次手术率或早期感染率。需要适当应用患者报告的预后指标来加强这些损伤治疗的证据基础。

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