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gene mutations are frequently detected in in situ follicular neoplasia.

作者信息

Schmidt Janine, Ramis-Zaldivar Joan Enric, Bonzheim Irina, Steinhilber Julia, Müller Inga, Haake Andrea, Yu Shan Chi, Raffeld Mark, Fend Falko, Salaverria Itziar, Siebert Reiner, Jaffe Elaine S, Quintanilla-Martinez Leticia

机构信息

Institute of Pathology and Neuropathology, Eberhard Karls University of Tübingen and Comprehensive Cancer Center, University Hospital Tübingen, Tübingen, Germany.

Hematopathology Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi iSunyer, Centro de Investigación Biomédica en Red Cáncer, Barcelona, Spain.

出版信息

Blood. 2018 Dec 20;132(25):2687-2690. doi: 10.1182/blood-2018-03-837039. Epub 2018 Nov 6.

DOI:10.1182/blood-2018-03-837039
PMID:30401710
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6302496/
Abstract
摘要

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gene mutations are frequently detected in in situ follicular neoplasia.原位滤泡性肿瘤中经常检测到基因突变。
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The pathobiology of follicular lymphoma.滤泡性淋巴瘤的病理生物学。
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本文引用的文献

1
Duodenal-type and nodal follicular lymphomas differ by their immune microenvironment rather than their mutation profiles.十二指肠型和结内型滤泡性淋巴瘤的免疫微环境不同，而不是突变谱不同。
Blood. 2018 Oct 18;132(16):1695-1702. doi: 10.1182/blood-2018-03-837252. Epub 2018 Aug 20.
2
Early loss of Crebbp confers malignant stem cell properties on lymphoid progenitors.Crebbp的早期缺失赋予淋巴祖细胞恶性干细胞特性。
Nat Cell Biol. 2017 Sep;19(9):1093-1104. doi: 10.1038/ncb3597. Epub 2017 Aug 21.
3
Next generation sequencing of the clonal IGH rearrangement detects ongoing mutations and interfollicular trafficking in in situ follicular neoplasia.克隆性IGH重排的下一代测序检测原位滤泡性肿瘤中正在进行的突变和滤泡间游走。
PLoS One. 2017 Jun 22;12(6):e0178503. doi: 10.1371/journal.pone.0178503. eCollection 2017.
4
Genome-wide analysis of pediatric-type follicular lymphoma reveals low genetic complexity and recurrent alterations of TNFRSF14 gene.儿童型滤泡性淋巴瘤的全基因组分析揭示了低遗传复杂性和TNFRSF14基因的复发性改变。
Blood. 2016 Aug 25;128(8):1101-11. doi: 10.1182/blood-2016-03-703819. Epub 2016 Jun 2.
5
The 2016 revision of the World Health Organization classification of lymphoid neoplasms.《世界卫生组织淋巴组织肿瘤分类（2016年修订版）》
Blood. 2016 May 19;127(20):2375-90. doi: 10.1182/blood-2016-01-643569. Epub 2016 Mar 15.
6
Genomic and epigenomic co-evolution in follicular lymphomas.滤泡性淋巴瘤中的基因组和表观基因组的共同进化。
Leukemia. 2015 Feb;29(2):456-63. doi: 10.1038/leu.2014.209. Epub 2014 Jul 16.
7
t(14;18) Translocation: A predictive blood biomarker for follicular lymphoma.t(14;18) 易位：滤泡性淋巴瘤的一种有预测作用的血液生物标志物。
J Clin Oncol. 2014 May 1;32(13):1347-55. doi: 10.1200/JCO.2013.52.8190. Epub 2014 Mar 31.
8
Early lesions of follicular lymphoma: a genetic perspective.滤泡性淋巴瘤的早期病变：遗传学视角
Haematologica. 2014 Mar;99(3):481-8. doi: 10.3324/haematol.2013.094474. Epub 2013 Oct 25.
9
Increasing genomic and epigenomic complexity in the clonal evolution from in situ to manifest t(14;18)-positive follicular lymphoma.在原位到表现为 t(14;18)阳性滤泡性淋巴瘤的克隆进化中，基因组和表观基因组复杂性增加。
Leukemia. 2014 May;28(5):1103-12. doi: 10.1038/leu.2013.307. Epub 2013 Oct 23.
10
EZH2 mutations are frequent and represent an early event in follicular lymphoma.EZH2 突变频繁，是滤泡性淋巴瘤的早期事件。
Blood. 2013 Oct 31;122(18):3165-8. doi: 10.1182/blood-2013-04-496893. Epub 2013 Sep 19.