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腹腔镜可调节胃束带术:食管癌发生的被低估的风险因素?-全国性调查。

Laparoscopic Adjustable Gastric Banding: an Underestimated Risk Factor for the Development of Esophageal Cancer?-a Nationwide Survey.

机构信息

Department of Visceral, Transplant and Thoracic Surgery, Center of Operative Medicine Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.

出版信息

Obes Surg. 2019 Feb;29(2):626-631. doi: 10.1007/s11695-018-3576-2.

DOI:10.1007/s11695-018-3576-2
PMID:30402803
Abstract

BACKGROUND

Approximately 14% of Austria's 8.5 million inhabitants have a body mass index (BMI) > 30 kg/m. The laparoscopic adjustable gastric banding (LAGB) was introduced in Austria in 1994, where about 10.300 patients have received it so far. One of our LAGB patients developed an adenocarcinoma of the distal esophagus 13 years after implantation.

OBJECTIVES

In order to calculate whether after LAGB patients are at higher risk for carcinoma of the esophagus, we performed a nationwide survey.

METHODS

A questionnaire was sent to all surgical departments in Austria, primarily in order to detect cases with esophageal carcinoma after LAGB, but also to evaluate the policy in Austria concerning preoperative work-up, operation, and follow-up in LAGB patients.

RESULTS

Since 1994, 37 of the 119 surgical departments in Austria have performed a total of about 10.300 LAGB implantations. Six patients have been identified with esophageal cancer following LAGB. The WHO statistical report on esophageal cancer shows an incidence of 2.8/100.000 per year in Austria, about 1/3 of which cases are adenocarcinoma of the distal esophagus.

CONCLUSION

Following LAGB, the incidence of esophageal cancer might be up to fivefold higher than the aged standardized overall population of Austria.

摘要

背景

奥地利有 850 万居民,其中约 14%的人体重指数(BMI)>30kg/m²。腹腔镜可调胃束带术(LAGB)于 1994 年在奥地利引入,迄今为止,约有 10300 名患者接受了该手术。我们的一位 LAGB 患者在植入 13 年后发展为远端食管腺癌。

目的

为了计算 LAGB 后患者是否有更高的食管癌风险,我们进行了一项全国性调查。

方法

向奥地利所有外科部门发送了一份问卷,主要是为了发现 LAGB 后发生食管癌的病例,同时评估奥地利在 LAGB 患者术前检查、手术和随访方面的政策。

结果

自 1994 年以来,奥地利的 119 个外科部门中有 37 个总共进行了约 10300 例 LAGB 植入术。有 6 名患者在 LAGB 后被诊断为食管癌。世界卫生组织关于食管癌的统计报告显示,奥地利每年的发病率为 2.8/100000,其中约 1/3 为远端食管腺癌。

结论

LAGB 后,食管癌的发病率可能比奥地利年龄标准化的总体人群高 5 倍。

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胃旁路术与单吻合口迷你胃旁路术治疗肥胖症减重手术后失败的挽救性治疗:系统综述和荟萃分析。
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Esophagogastric Neoplasms Following Bariatric Surgery: an Updated Systematic Review.减重手术后的胃食管肿瘤:更新的系统性综述。
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