Zhu Hai-Feng, Wang Gang-Liang, Zhou Zhi-Jie, Fan Shun-Wu
Department of Orthopedics, Sir Run Run Shaw Hospital, Medical College of Zhejiang University, Hangzhou, China.
Orthop Surg. 2018 Nov;10(4):296-305. doi: 10.1111/os.12402. Epub 2018 Nov 7.
To compare postoperative imaging results, clinical outcomes and complications between the multifidus muscle bundle (MMB) approach and the conventional open (CO) approach in one-level posterior lumbar interbody fusion (PLIF).
Based on the inclusion and exclusion criteria, 201 of 351 patients in our hospital were enrolled in this prospective study and underwent MMB-PLIF or CO-PLIF randomly: 111 patients in the MMB-PLIF group and 90 patients in the CO-PLIF group. A total of 100 patients failed to be followed up in the following 7-9 years. Therefore, in this study, 52 patients of the MMB group and 49 patients of the CO group were included. We evaluated the differences in terms of multifidus atrophy rate, intervertebral disc height and segmental lordosis restoration of the operation segment, lumbar lordosis restoration, fusion rate, visual analogue scale (VAS) for back and leg pain, Oswestry disability index (ODI), complication rates, and patient satisfaction rates between the two groups. Correlation between multifidus muscle degeneration and the incidence of complications was investigated, and we compared the multifidus muscle degeneration rate between patients with or without intractable back pain or adjacent segment degeneration.
There were no significant differences in age, sex, body mass index (BMI), diagnosis, segments distribution, and mean follow-up time between the MMB-PLIF group and the CO-PLIF group. In addition, no differences regarding sex, age, or BMI were found between the lost follow-up group and the successful follow-up group. In regard to imaging and clinical evaluation, at the final follow-up, there were significant differences in multifidus atrophy rates (27.0% ± 6.8% vs 38.7% ± 10.9%), lumbar lordosis restoration (4.6° ± 2.5° vs 3.0° ± 1.9°), postoperative VAS for back pain (1.1 ± 0.9 vs 1.8 ± 1.2), ODI (7.7 ± 5.0 vs 12.4 ± 6.7), and patient satisfaction rates (86.5% vs 61.2%) between MMB-PLIF and CO-PLIF groups. However, there were no significant differences in segmental lordosis, intervertebral height restoration, postoperative VAS for leg pain or fusion rate between the two groups. In regards to complications, there were significant differences in the incidence of adjacent segment degeneration (3.8% vs 14.3%), intractable back pain (3.8% vs 22.4%), and residual neurological symptoms (5.8% vs 20.4%) between the two groups (P < 0.05) at the final follow-up. In addition, patients with adjacent segment degeneration and intractable back pain were observed with more significant multifidus muscle atrophy than those without these two complications (31.9% ± 1.1% vs 39.6% ± 2.1% and 30.9% ± 1.1% vs 42.8% ± 2.1%).
Compared with CO-PLIF, MMB-PLIF had advantages in relation to protection of the multifidus muscle, better maintenance of lumbar lordosis, reduced lower back pain and ODI score, fewer complications, and a higher patient satisfaction rate. Protection of the multifidus muscle in lumbar surgery is an important aspect of minimally invasive surgery.
比较多裂肌束(MMB)入路与传统开放(CO)入路在单节段腰椎后路椎间融合术(PLIF)中的术后影像学结果、临床疗效及并发症情况。
根据纳入和排除标准,我院351例患者中的201例纳入本前瞻性研究,并随机接受MMB-PLIF或CO-PLIF手术:MMB-PLIF组111例患者,CO-PLIF组90例患者。共有100例患者在接下来的7-9年中失访。因此,本研究纳入MMB组52例患者和CO组49例患者。我们评估了两组在多裂肌萎缩率、手术节段的椎间盘高度和节段性前凸恢复、腰椎前凸恢复、融合率、腰背痛和腿痛的视觉模拟评分(VAS)、Oswestry功能障碍指数(ODI)、并发症发生率及患者满意率方面的差异。研究多裂肌退变与并发症发生率之间的相关性,并比较有无顽固性腰背痛或相邻节段退变患者的多裂肌退变率。
MMB-PLIF组与CO-PLIF组在年龄、性别、体重指数(BMI)、诊断、节段分布及平均随访时间方面无显著差异。此外,失访组与成功随访组在性别、年龄或BMI方面也无差异。在影像学和临床评估方面,末次随访时,MMB-PLIF组与CO-PLIF组在多裂肌萎缩率(27.0%±6.8%对38.7%±10.9%)、腰椎前凸恢复(4.6°±2.5°对3.0°±1.9°)、术后腰背痛VAS(1.1±0.9对1.8±1.2)、ODI(7.7±5.0对12.4±6.7)及患者满意率(86.5%对61.2%)方面存在显著差异。然而,两组在节段性前凸、椎间高度恢复、术后腿痛VAS或融合率方面无显著差异。在并发症方面,末次随访时两组在相邻节段退变发生率(3.8%对14.3%)、顽固性腰背痛(3.8%对22.4%)及残留神经症状(5.8%对20.4%)方面存在显著差异(P<0.05)。此外,观察到有相邻节段退变和顽固性腰背痛的患者比无这两种并发症的患者多裂肌萎缩更明显(31.9%±1.1%对39.6%±2.1%以及30.9%±1.1%对42.8%±2.1%)。
与CO-PLIF相比,MMB-PLIF在保护多裂肌、更好地维持腰椎前凸、减轻下腰痛和ODI评分、减少并发症及提高患者满意率方面具有优势。腰椎手术中保护多裂肌是微创手术的一个重要方面。