Li Juan, Chang Xiao Yan, Zhu Liang, Dai Meng Hua, Xue Hua Dan
Department of Radiology, PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
Department of Pathology, PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2018 Oct 30;40(5):714-718. doi: 10.3881/j.issn.1000-503X.10382.
Acinar cell carcinoma of pancreas(ACCP)is a rare pancreatic exocrine tumor that accounts for about 1% of pancreatic tumors. The typical imaging manifestations of ACCP are as follows:(1)the tumor is large in volume,partially or completely exophytic;(2)complete or incomplete capsule is visible with thin linear enhancement;(3)CT density and MRI signal:plain CT images reveals that the tumors have similar or slightly hypodense densities relative to the adjacent normal pancreas,the solid part of ACCP has low to intermediate signal intensity on T1WI and intermediate to high signal intensity on T2WI compared with the surrounding normal pancreas;(4)pattern of enhancement:tumors exhibit heterogeneous enhancement and it is less than that in the surrounding normal pancreas;(5)fissure-like,swirling necrosis that may be a characteristic change of tumor;(6)pancreatic and biliary duct dilatation is rare;(7)adjacent organs and blood vessels around the pancreas may be invaded;(8)distant metastasis of liver and other parts may be observed;(9)PET-CT shows high FDG uptake. An ACCP patient with atypical imaging manifestations was treated in Peking Union Medical College Hospital from November 2015 to August 2017. The lesion manifested iso-enhancement and many imaging examinations failed to find the tumor. The patient ultimately underwent surgery and diagnosed as ACCP by pathology.
胰腺腺泡细胞癌(ACCP)是一种罕见的胰腺外分泌肿瘤,约占胰腺肿瘤的1%。ACCP的典型影像学表现如下:(1)肿瘤体积较大,部分或完全向外生长;(2)可见完整或不完整的包膜,有薄的线状强化;(3)CT密度和MRI信号:CT平扫图像显示肿瘤相对于相邻正常胰腺密度相似或略低密度,ACCP的实性部分在T1WI上相对于周围正常胰腺呈低到中等信号强度,在T2WI上呈中等至高信号强度;(4)强化方式:肿瘤表现为不均匀强化,且低于周围正常胰腺;(5)裂隙样、漩涡状坏死可能是肿瘤的特征性改变;(6)胰腺和胆管扩张少见;(7)胰腺周围的相邻器官和血管可能受侵犯;(8)可能观察到肝和其他部位的远处转移;(9)PET-CT显示FDG高摄取。2015年11月至2017年8月,北京协和医院收治了1例具有非典型影像学表现的ACCP患者。病变表现为等强化,多次影像学检查均未发现肿瘤。患者最终接受手术,病理诊断为ACCP。