Mednax Incorporated, Sunrise, Florida
Mednax Incorporated, Sunrise, Florida.
Pediatrics. 2018 Dec;142(6). doi: 10.1542/peds.2018-1839. Epub 2018 Nov 7.
Neonatal abstinence syndrome (NAS) is increasing in incidence and most commonly associated with maternal opioid use during pregnancy. Nonopioid alternatives to treat opioid dependence are highly sought after in the country's current opioid epidemic. Whether Kratom, a legal, widely available herbal supplement, should be classified as an opioid is contentious. Although the US Food and Drug Administration has recently addressed this controversy, Kratom continues to be marketed as a nonopioid remedy for opioid withdrawal. Its use is increasing in the United States. We describe an infant with NAS born to a mother with daily Kratom tea ingestion to self-treat opioid dependence. Pediatricians and parents should be aware of the risk of NAS due to Kratom use during pregnancy.
新生儿戒断综合征(NAS)的发病率正在上升,与孕妇在怀孕期间使用阿片类药物的情况最为常见。在该国目前的阿片类药物流行中,人们非常希望寻找非阿片类药物替代物来治疗阿片类药物依赖。是否将卡痛,一种合法的、广泛使用的草药补充剂,归类为阿片类药物存在争议。尽管美国食品和药物管理局最近已经解决了这一争议,但卡痛仍被作为一种非阿片类药物治疗阿片类药物戒断的方法进行销售。它在美国的使用正在增加。我们描述了一例新生儿戒断综合征的婴儿,其母亲每天饮用卡痛茶以自我治疗阿片类药物依赖。儿科医生和家长应该意识到由于怀孕期间使用卡痛而导致 NAS 的风险。