天然药物，效果却不那么天然：“ kratom”导致的新生儿戒断综合征
Natural drugs, not so natural effects: Neonatal abstinence syndrome secondary to 'kratom'.
作者信息
Davidson L, Rawat M, Stojanovski S, Chandrasekharan P
机构信息
Division of Neonatology, Department of Pediatrics, University at Buffalo, Oishei Children's Hospital, Buffalo, NY, USA.
Department of Pharmacy, Oishei Children's Hospital, Buffalo, NY, USA.
出版信息
J Neonatal Perinatal Med. 2019;12(1):109-112. doi: 10.3233/NPM-1863.
BACKGROUND
Mitragyna speciosa, also known as kratom, is obtained from the coffee plant family 'Rubiaceae.' Kratom is available in the form of capsules, whole, processed and powdered leaves, and as liquids. Secondary to its 'natural herb' status and opioid effects, it is misconceived to be a safe alternative for the treatment of chronic pain. The use of kratom has increased by tenfold in the United States since 2010.
METHODS AND RESULTS
We report a term neonate who was born to a chronic kratom user and required treatment with opiates for neonatal drug withdrawal.
CONCLUSION
Physicians should be aware of these herbal supplements and its potential withdrawal effects in newborn which cannot be picked up by the standard toxicology screen.
背景
帽柱木，又称“ kratom”，源自茜草科咖啡属植物。Kratom有胶囊、整叶、加工叶、粉末状叶片以及液体等形式。由于其“天然草药”的身份和阿片样作用，它被误解为治疗慢性疼痛的安全替代品。自2010年以来，美国Kratom的使用量增长了十倍。
方法与结果
我们报告了一名足月新生儿，其母亲为慢性Kratom使用者，该新生儿因新生儿药物戒断需要使用阿片类药物进行治疗。
结论
医生应了解这些草药补充剂及其在新生儿中潜在的戒断效应，而这些效应无法通过标准毒理学筛查检测出来。
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