Chopra P S, Bass J, Dacumos G C, Dufek J H, Rawlings C A, Kahn D R
J Cardiovasc Surg (Torino). 1977 Sep-Oct;18(5):519-22.
Femoral artery grafts were anastomosed end-to-end to the left internal mammary artery proximally and end-to-side to the circumflex coronary artery distally in 21 adult mongrel dogs. Fourteen dogs received allografts and seven received autografts. All autografts studied from one to 11 months were patent. Eleven of the fourteen homografts studied from one to thirteen months were occluded. Histologically, extensive interstitial edema and leukocytic infiltration with subintimal fibrosis and thrombotic occlusion were seen. This study shows that fresh arterial autografts have excellent long term patency, but that most arterial allografts have early thrombotic occlusion.
在21只成年杂种犬中，将股动脉移植物近端与左乳内动脉端端吻合，远端与旋支冠状动脉端侧吻合。14只犬接受同种异体移植物，7只接受自体移植物。所有研究的自体移植物在1至11个月内均保持通畅。14只同种异体移植物中，有11只在1至13个月的研究中发生闭塞。组织学检查可见广泛的间质水肿、白细胞浸润伴内膜下纤维化和血栓闭塞。本研究表明，新鲜动脉自体移植物具有良好的长期通畅性，但大多数动脉同种异体移植物早期会发生血栓闭塞。
