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源于Zenker憩室的鳞状细胞癌:一例报告并文献复习

Squamous Cell Carcinoma Arising in Zenker's Diverticulum: A Case Report and Review of the Literature.

作者信息

Hajjar Waseem M, Almutairi Othman T, Jameel Mohammed A, Al-Nassar Sami A, Raddaoui Emad, Hajjar Adnan W

机构信息

Department of Surgery, Division of Thoracic Surgery, King Khalid University School of Medicine Hospital, Riyadh, Saudi Arabia.

Department of Pathology, Alfaisal University School of Medicine, Riyadh, Saudi Arabia.

出版信息

Turk Thorac J. 2018 Jun 19;19(4):228-230. doi: 10.5152/TurkThoracJ.2018.17082. Print 2018 Oct.

DOI:10.5152/TurkThoracJ.2018.17082
PMID:30407159
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6196899/
Abstract

The occurrence of squamous cell carcinoma (SCC) arising in a Zenker's diverticulum is a very rare incident. Complete excision of the diverticulum is considered as the procedure of choice for SCC in the pharyngeal pouch. Histopathological assessment of the pouch is the only modality to rule out SCC. Here, we report a case of a 71-year-old male with 20 years of history of Zenker's diverticulum, who recently presented with a history of weight and appetite loss. A barium swallow confirmed Zenker's pouch, the patient underwent diver-ticulectomy and cricopharyngeal myotomy; a histopathological examination of the specimen revealed a fungating mass of SCC within the pouch. This report highlights the suggestion of considering SCC not only in patients with a long history of Zenker's diverticulum but also when there is a clinical suspicion with new symptoms for a more aggressive management for diagnosis and complete excision of the pouch.

摘要

在Zenker憩室中发生鳞状细胞癌(SCC)是非常罕见的情况。憩室的完整切除被认为是咽袋SCC的首选治疗方法。对咽袋进行组织病理学评估是排除SCC的唯一方法。在此,我们报告一例71岁男性,有20年Zenker憩室病史,近期出现体重减轻和食欲减退。吞钡检查证实为Zenker憩室,患者接受了憩室切除术和环咽肌切开术;标本的组织病理学检查显示憩室内有一个溃疡性SCC肿块。本报告强调,不仅对于有长期Zenker憩室病史的患者,而且当临床上怀疑有新症状时,都应考虑SCC,以便进行更积极的管理,从而诊断并完整切除咽袋。

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