Paramalingam Shereen, Dyke Jason M, Nossent Johannes C
Department of Rheumatology, Sir Charles Gairdner Hospital, Nedlans, Australia.
University of Western Australia School of Medicine, Crawley, Australia.
Eur J Rheumatol. 2018 Nov 6;6(2):105-107. doi: 10.5152/eurjrheum.2018.18071. Print 2019 Apr.
Sporadic late onset nemaline myopathy (SLONM) is a rare, intractable acquired myopathy that is characterised by progressive muscle weakness and the presence of nemaline rods in myofibres. Unlike the congenital form of nemaline myopathy (NM), there are only few case reports and series on SLONM in the scientific literature. We present a case report of SLONM in a 62-year-old male from a rural town in Western Australia, without any of the conditions often associated with SLONM such as monoclonal gammopathy of uncertain significance or HIV infection. SLONM should be considered in the differential diagnosis of progressive proximal muscle weakness in an adult.
散发性晚发型杆状体肌病（SLONM）是一种罕见的、难治性获得性肌病，其特征为进行性肌无力以及肌纤维中存在杆状体。与先天性杆状体肌病（NM）不同，科学文献中关于SLONM的病例报告和系列报道很少。我们报告一例来自西澳大利亚州一个乡村小镇的62岁男性SLONM病例，该患者没有任何通常与SLONM相关的疾病，如意义未明的单克隆丙种球蛋白病或HIV感染。在鉴别诊断成人进行性近端肌无力时应考虑SLONM。
