Lino-Silva Leonardo Saúl, León-Takahashi Alberto, López-Basave Horacio, Padilla-Rosciano Alejandro, Miranda-Dévora Gerardo, Granados-García Martín, Salcedo-Hernández Rosa
Secretaría de Salud, Instituto Nacional de Cancerología, Ciudad de México, México.
Gac Med Mex. 2018;154(5):598-604. doi: 10.24875/GMM.18003411.
Traditionally, carcinoma classifications have been based on clinical or pathological features. However, with the development of molecular biology in recent decades, more tumors are increasingly being genetically studied and, in several of them, molecular classifications have been created (the most widely studied and used is that for breast cancer). Colon and rectum cancer are no exception. In this short review, the evolution of colon and rectum cancer molecular classification is explained and the consensus conclusions on the subject are addressed.
传统上，癌症分类是基于临床或病理特征。然而，近几十年来随着分子生物学的发展，越来越多的肿瘤接受了基因研究，其中一些肿瘤已经建立了分子分类（研究和应用最广泛的是乳腺癌分子分类）。结肠癌和直肠癌也不例外。在这篇简短的综述中，解释了结肠癌和直肠癌分子分类的演变，并阐述了关于该主题的共识结论。
