Division of Neurosurgery, University of Vermont Medical Center, Burlington, Vermont.
Department of Neurosurgery, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Curr Opin Pediatr. 2018 Dec;30(6):786-790. doi: 10.1097/MOP.0000000000000679.
With increasing use of MRI, more patients are being diagnosed with Chiari I malformation (CM1), many of whom are asymptomatic. When symptoms are present, headache is the most frequent presenting feature, although symptoms can be variable. The purpose of this review is to help primary care clinicians better understand the relationship between an individual's presenting symptoms and the presence of radiographic CM1, and to describe the expected outcomes for patients who undergo decompression surgery.
Recent literature has shown that asymptomatic patients with CM1 tend to have a benign natural history. For symptomatic Chiari malformation, headache is the most common presenting symptom and the majority of patients that present with headache will have symptom improvement after foramen magnum decompression. This improvement is most reliable for patients with classic Chiari-type headache, which are described as occipital or cervical and tussive in nature, but has also been shown in patients with atypical headaches who have undergone surgery.
CM1 is a common radiographic finding and associated symptoms can be variable. The relevance of this finding to a particular patient and need for intervention must be made on an individual basis.
随着 MRI 的广泛应用,越来越多的患者被诊断为 Chiari I 畸形(CM1),其中许多患者无症状。当出现症状时,头痛是最常见的表现特征,尽管症状可能多种多样。本文的目的是帮助初级保健临床医生更好地理解个体的症状表现与影像学 CM1 之间的关系,并描述接受减压手术患者的预期结果。
最近的文献表明,无症状的 CM1 患者倾向于具有良性的自然病史。对于有症状的 Chiari 畸形,头痛是最常见的症状表现,大多数头痛患者在进行枕骨大孔减压后症状会有所改善。对于经典 Chiari 型头痛患者,这种改善最为可靠,这种头痛表现为枕部或颈部,且具有咳嗽性质,但在接受手术的非典型头痛患者中也有显示。
CM1 是一种常见的影像学发现,相关症状可能多种多样。必须根据个体情况确定该发现与特定患者的相关性及其干预需求。