Penn Chronobiology, Howard Hughes Medical Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Penn Chronobiology, Howard Hughes Medical Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Neuron. 2018 Nov 7;100(3):514-516. doi: 10.1016/j.neuron.2018.10.030.
Prolonged wakefulness stimulates the homeostatic need to sleep, but transition to sleep also depends on the circadian time of day. However, links between circadian and homeostatic influences are not well understood. Guo et al. (2018) identify a Drosophila circuit connecting circadian clock neurons to sleep-promoting ring neurons in the ellipsoid body.
长时间的清醒会刺激人体产生睡眠的生理需求,但进入睡眠状态也依赖于一天中的生物钟时间。然而,生物钟和生理需求的影响之间的联系还不是很清楚。郭等人(2018 年)在果蝇中发现了一个连接生物钟神经元和位于椭圆体中的促睡眠神经元的回路。