肢端肥大症中的广泛性周围神经功能障碍：一项采用传统和新型神经生理学技术的研究
Generalised peripheral nerve dysfunction in acromegaly: a study by conventional and novel neurophysiological techniques.
作者信息
Jamal G A, Kerr D J, McLellan A R, Weir A I, Davies D L
出版信息
J Neurol Neurosurg Psychiatry. 1987 Jul;50(7):886-94. doi: 10.1136/jnnp.50.7.886.
Abstract
Twenty four patients with clinical, radiological and biochemical evidence of acromegaly were investigated by a number of independent neurophysiological tests. Two-thirds of the patients showed evidence of generalised peripheral nerve dysfunction. A significant correlation was found between total exchangeable body sodium, an indicator of disease activity, and the severity of the neuropathy. The generalised peripheral nerve abnormality was found to occur independently of the associated carbohydrate intolerance human growth hormone levels and other endocrinological dysfunction in this disorder.
摘要
对24例有肢端肥大症临床、放射学和生化证据的患者进行了多项独立的神经生理学检查。三分之二的患者有全身周围神经功能障碍的证据。发现可交换体钠总量（疾病活动的一个指标）与神经病变的严重程度之间存在显著相关性。在这种疾病中，全身周围神经异常被发现独立于相关的碳水化合物不耐受、人类生长激素水平及其他内分泌功能障碍而发生。
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Generalised peripheral nerve dysfunction in acromegaly: a study by conventional and novel neurophysiological techniques.肢端肥大症中的广泛性周围神经功能障碍：一项采用传统和新型神经生理学技术的研究
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