Jelinski Murray, Marti Sonia, Janzen Eugene, Schwartzkopf-Genswein Karen
Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4 (Jelinski); University of Calgary Ringgold Standard Institution - Animal Production Health, 2500 University Drive NW, Calgary, Alberta T2N 1N4 (Marti); Clinical Practice, Faculty of Veterinary Medicine, Calgary, Alberta T2N 1N4 (Janzen); Agriculture and Agri-food Canada - Lethbridge Research Centre, Lethbridge, Alberta (Schwartzkopf-Genswein).
Can Vet J. 2018 Nov;59(11):1202-1208.
This investigation followed a cohort ( = 21) of single-sourced Angus cross yearling heifers diagnosed with toe tip necrosis syndrome (TTNS). The animals were intensively followed for ~7 months, over which time 5 animals were euthanized because of intractable lameness or life-threatening sequelae such as cellulitis and myositis. Treatment consisted of systemic antimicrobial and nonsteroidal anti-inflammatory therapy, removing the necrotic horn tissue to facilitate drainage, and relocating the cattle to an earthen-floor pen. Sixteen of the 21 heifers recovered uneventfully. Upon sectioning the feet after slaughter, all the foot lesions had healed, but in some instances, the 3rd phalangeal bone had undergone bone remodeling, indicative of an earlier pathological process. This study is unique in that it chronicled the clinical and pathological outcomes associated with TTNS over an extended period.
本研究跟踪了一群（n = 21）被诊断患有趾尖坏死综合征（TTNS）的单源安格斯杂交一岁小母牛。对这些动物进行了约7个月的密切跟踪，在此期间，有5头动物因顽固性跛行或危及生命的后遗症（如蜂窝织炎和肌炎）而被安乐死。治疗包括全身抗菌和非甾体抗炎治疗，切除坏死的角组织以促进引流，并将牛转移到泥土地面的围栏中。21头小母牛中有16头顺利康复。屠宰后对足部进行切片检查时，所有足部病变均已愈合，但在某些情况下，第三趾骨发生了骨重塑，这表明早期存在病理过程。这项研究的独特之处在于，它长期记录了与TTNS相关的临床和病理结果。
