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杜氏肌营养不良症成年患者采用骶管硬膜外阻滞而非全身麻醉。

Caudal epidural block instead of general anesthesia in an adult with Duchenne muscular dystrophy.

作者信息

Shafy Shabana Z, Hakim Mohammed, Villalobos Mauricio Arce, Pearson Gregory D, Veneziano Giorgio, Tobias Joseph D

机构信息

Department of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, OH, USA,

Department of Plastic Surgery, Nationwide Children's Hospital, Columbus, OH, USA.

出版信息

Local Reg Anesth. 2018 Oct 15;11:75-80. doi: 10.2147/LRA.S180867. eCollection 2018.

Abstract

Duchenne muscular dystrophy (DMD), first described in 1834, is an X-linked dystrophinopathy, leading to early onset skeletal muscle weakness. Life expectancy is reduced to early adulthood as a result of involvement of voluntary skeletal muscles with respiratory failure, orthopedic deformities, and associated cardiomyopathy. Given its multisystem involvement, surgical intervention may be required to address the sequelae of the disease process. We present a 36-year-old adult with DMD, who required anesthetic care during surgical debridement of an ischial pressure sore. Given his significant respiratory muscle involvement, ultrasound-guided caudal epidural anesthesia was used instead of general during the surgical procedure. The technique and its applications are discussed, with particular emphasis on the feasibility and safety of using regional anesthetic techniques in patients with DMD.

摘要

杜氏肌营养不良症(DMD)于1834年首次被描述,是一种X连锁肌营养不良症,会导致早期出现骨骼肌无力。由于随意骨骼肌受累并伴有呼吸衰竭、骨科畸形及相关心肌病,预期寿命缩短至成年早期。鉴于其多系统受累,可能需要手术干预来处理疾病过程的后遗症。我们报告一名36岁的成年DMD患者,其在坐骨压力性溃疡手术清创期间需要麻醉护理。鉴于他的呼吸肌严重受累,手术过程中使用超声引导下骶管硬膜外麻醉替代全身麻醉。本文讨论了该技术及其应用,特别强调了在DMD患者中使用区域麻醉技术的可行性和安全性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8170/6197695/f8e84d33b0f4/lra-11-075Fig1.jpg

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