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澳大利亚癫痫女性的剖宫产情况。

Cesarean section in Australian women with epilepsy.

作者信息

Vajda Frank John Emery, O'Brien Terence John, Graham Janet Elizabeth, Hitchcock Alison Anne, Kuhn Raphael John Paul, Lander Cecilie Margaret, Eadie Mervyn John

机构信息

Department of Medicine and Neurosciences, Royal Melbourne Hospital and University of Melbourne, Parkville, Victoria 3050, Australia.

Department of Medicine and Neurosciences, Alfred Hospital and Monash University, Melbourne 3004, Australia.

出版信息

Epilepsy Behav. 2018 Dec;89:126-129. doi: 10.1016/j.yebeh.2018.10.008. Epub 2018 Nov 7.

Abstract

The literature suggests that cesarean delivery or birth is carried out more often in pregnant women with epilepsy (WWE) than in pregnant women in the general population. Data were utilized from the Australian Pregnancy Register (APR) for Women on Antiepileptic Medication to investigate this issue in Australia. Over almost two decades, the mean CS rate in 1900 APR women was 39.2%, but was only 29.9% in women in the general population (relative risk (R.R.) = 1.31, 95% confidence interval (C.I.) 1.24, 1.39). Rates for forceps and suction-assisted delivery were similar in the two datasets. The 9.3% excess CS rate was almost entirely accounted for by operations carried out prior to the onset of labor. The rates for CS during labor were very similar. Only 11.0% of the WWE knew the indication for their prelabor CS, whereas 69.8% knew why theirs had been carried out during labor (odds ratio (O.R.) = 0.054; 99% C.I. 0.032, 0.089). Slightly older mothers and increased proportions of primipara probably made small contributions to the increased prelabor CS rate in the Australian WWE, but most of the excess could not be accounted for in the Register data. Australian obstetricians may have tended to regard prelabor CS as a preferable course of action in managing delivery in WWE, even in the absence of other indications.

摘要

文献表明,癫痫孕妇(WWE)进行剖宫产分娩的频率高于普通孕妇。利用澳大利亚抗癫痫药物孕妇登记册(APR)的数据来调查澳大利亚的这一问题。在近二十年里,1900名APR女性的平均剖宫产率为39.2%,而普通女性仅为29.9%(相对风险(R.R.)=1.31,95%置信区间(C.I.)1.24,1.39)。两个数据集中产钳和吸引助产的发生率相似。剖宫产率高出9.3%几乎完全是由临产前进行的手术导致的。分娩期间的剖宫产率非常相似。只有11.0%的癫痫孕妇知道她们临产前剖宫产的指征,而69.8%的人知道她们分娩期间剖宫产的原因(优势比(O.R.)=0.054;99%置信区间0.032,0.089)。年龄稍大的母亲和初产妇比例增加可能对澳大利亚癫痫孕妇临产前剖宫产率的增加有微小贡献,但登记数据无法解释大部分超额情况。澳大利亚产科医生可能倾向于将临产前剖宫产视为管理癫痫孕妇分娩的首选行动方案,即使没有其他指征。

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