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2型糖尿病患者的药物依从性和糖尿病自我护理活动

Medication Adherence and Diabetes Self-Care Activities Among Patients With Type 2 Diabetes Mellitus.

作者信息

Jannoo Zeinab, Mamode Khan Naushad

机构信息

Department of Economics and Statistics, University of Mauritius, Réduit, Mauritius.

Department of Economics and Statistics, University of Mauritius, Réduit, Mauritius.

出版信息

Value Health Reg Issues. 2019 May;18:30-35. doi: 10.1016/j.vhri.2018.06.003. Epub 2018 Nov 9.

Abstract

BACKGROUND

The prevalence of type 2 diabetes mellitus (T2DM) is increasing at an alarming rate in developing countries. The accompanying complications of T2DM can be reduced by maintaining a good adherence to medication and self-care activities.

OBJECTIVES

To evaluate medication adherence and self-care behaviors among patients with T2DM.

METHODS

A total of 497 subjects with T2DM were recruited from three hospitals and a government clinic in the state of Selangor, Malaysia. Previously validated scales were used to measure medication adherence (Morisky Medication Adherence Scale) and diabetes self-care activities (Summary of Diabetes Self-Care Activities). Pearson correlation coefficient was used to investigate the relationship between the risk factors and medication adherence. Pearson χ test of association was used to test significant association.

RESULTS

The mean age of the subjects was 55.5 years. The mean Morisky Medication Adherence Scale score was 5.65 ± 1.97, indicating a moderate adherence level to medication. Among the subjects who had low adherence level, 50.9% were Malays, followed by 34.2% Indians. The Pearson χ test of association indicated a significant association (P = 0.000) between ethnicity and medication adherence. The subjects had better self-care behaviors in their general diet (mean 5.04 ± 1.88) and poor self-care behaviors in blood sugar testing (mean 2.13 ± 2.34).

CONCLUSIONS

The Malaysians had a moderate medication adherence level, whereas they were nonadherent to blood glucose testing. Emphasis on self-care activities and medication adherence is relevant to improve outcomes in the management of T2DM.

摘要

背景

在发展中国家,2型糖尿病(T2DM)的患病率正以惊人的速度上升。通过保持良好的药物依从性和自我护理活动,可以减少T2DM的相关并发症。

目的

评估T2DM患者的药物依从性和自我护理行为。

方法

从马来西亚雪兰莪州的三家医院和一家政府诊所招募了总共497名T2DM患者。使用先前验证过的量表来测量药物依从性(Morisky药物依从性量表)和糖尿病自我护理活动(糖尿病自我护理活动总结)。采用Pearson相关系数来研究危险因素与药物依从性之间的关系。采用Pearsonχ²关联检验来检验显著关联。

结果

受试者的平均年龄为55.5岁。Morisky药物依从性量表的平均得分为5.65±1.97,表明药物依从性处于中等水平。在依从性低的受试者中,50.9%为马来人,其次是34.2%为印度人。Pearsonχ²关联检验表明种族与药物依从性之间存在显著关联(P = 0.000)。受试者在总体饮食方面的自我护理行为较好(平均5.04± 1.88),而在血糖检测方面的自我护理行为较差(平均2.13± 2.34)。

结论

马来西亚人的药物依从性处于中等水平,而他们在血糖检测方面依从性较差。强调自我护理活动和药物依从性对于改善T2DM管理的结果具有重要意义。

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