Abdullah Nor Fadhilah, Khuan Lee, Theng Cheong Ai, Sowtali Siti Noorkhairina, Juni Muhamad Hanafiah
a Department of Nursing and Rehabilitation, Faculty of Medicine and Health Sciences , Universiti Putra Malaysia , Serdang 43400 , Selangor , Malaysia.
b Department of Nursing, Faculty of Medicine , Universiti Sultan Zainal Abidin , Gong Badak 21300 , Terengganu , Malaysia.
Contemp Nurse. 2019 Feb;55(1):27-37. doi: 10.1080/10376178.2019.1583067. Epub 2019 Feb 21.
The prevalence of diabetes mellitus (DM) is steadily increasing worldwide, with a significant DM population in Asian countries. Adherence to medications is important to achieve good glycaemic control among patients with DM. Thus, patients' adherence to their medication regimen should be determined to optimise DM management. To determine medication adherence and the relationship between patient profile and medication adherence among patients with type 2 DM (T2DM). Cross-sectional survey. This study was conducted in a public hospital in Selangor, Malaysia, from December 2016 to June 2017. Data was obtained through administration of the Medication Compliance Questionnaire and an electronic medical records database. Multivariate logistic regression analysis was used to determine the predictors of medication adherence. A total of 232 (95.9% response rate) patients participated in this study. The overall percentage of medication adherence among patients with DM was 55.2%. The majority of participants were female (53.4%), Malay (47.0%), aged 41-64 years (55.2%; mean age, 56.69 years), married (84.5%), unemployed (60.8%) and attended secondary school (53.9%). The factors independently associated with adherence were ethnicity (odds ratio [OR], 1.43; 95% confidence interval [CI]: 1.03-1.99) and haemoglobin A1c (HbA1c) level (OR, 2.71; 95% CI: 1.56-4.72). The medication adherence among patients with DM in a public hospital in Selangor, Malaysia was low. A health intervention emphasising patient-centred care is warranted to improve DM patients' adherence to prescribed medication. Considering that Malaysia has a multi-ethnic population, the patients' ethnicity and their HbA1c levels need to be considered in the implementation of any intervention to improve medication adherence. Medication adherence is influenced by individual patients' characteristics. To improve adherence to the medication regimen, nurses should consider patients' profiles.
糖尿病（DM）在全球范围内的患病率正在稳步上升，亚洲国家有大量的糖尿病患者。坚持用药对于糖尿病患者实现良好的血糖控制至关重要。因此，应确定患者对药物治疗方案的依从性，以优化糖尿病管理。为了确定2型糖尿病（T2DM）患者的用药依从性以及患者特征与用药依从性之间的关系。横断面调查。本研究于2016年12月至2017年6月在马来西亚雪兰莪州的一家公立医院进行。通过发放药物依从性问卷和电子病历数据库获取数据。采用多因素逻辑回归分析来确定用药依从性的预测因素。共有232名患者（应答率为95.9%）参与了本研究。糖尿病患者的总体用药依从率为55.2%。大多数参与者为女性（53.4%）、马来人（47.0%）、年龄在41 - 64岁之间（55.2%；平均年龄56.69岁）、已婚（84.5%）、失业（60.8%）且接受过中学教育（53.9%）。与依从性独立相关的因素是种族（比值比[OR]，1.43；95%置信区间[CI]：1.03 - 1.99）和糖化血红蛋白（HbA1c）水平（OR，2.71；95% CI：1.56 - 4.72）。马来西亚雪兰莪州一家公立医院的糖尿病患者用药依从性较低。有必要进行以患者为中心的健康干预，以提高糖尿病患者对规定药物的依从性。鉴于马来西亚是一个多民族国家，在实施任何改善用药依从性的干预措施时，都需要考虑患者的种族及其HbA1c水平。用药依从性受个体患者特征的影响。为了提高对药物治疗方案的依从性，护士应考虑患者的特征。
