Daneault S, Infante-Rivard C
Département de santé communautaire, hôpital Maison-neuve-Rosemont, université, de Montréal, PQ.
CMAJ. 1988 Aug 15;139(4):297-304.
Review of the literature reveals sporadic but true increases in the prevalence and death rates for asthma over the past 25 years. Although changes in hereditary, allergic and environmental factors must be considered as possible causes of this increase, its suddenness points to risk factors that change rapidly. Such is the case with atmospheric pollutants, notably nitrogen dioxide and particles, both of which have been shown to have adverse effects on the tracheobronchial tree. These pollutants tend to concentrate inside homes, especially since the early 1980s, when the energy crisis brought about changes in the home environment.
文献综述显示,在过去25年中,哮喘的患病率和死亡率虽呈零星但确实的增长。尽管遗传、过敏和环境因素的变化必须被视为这种增长的可能原因,但其突然性指向了迅速变化的风险因素。大气污染物就是这种情况,尤其是二氧化氮和颗粒物,两者都已被证明对气管支气管树有不良影响。这些污染物往往集中在家庭内部,特别是自20世纪80年代初以来,当时能源危机导致家庭环境发生了变化。