Liu Yifang, Liu Ruimin, Wang Xiang, Jiang Jiaxin, Li Wenwang, Liu Juan, Guo Shumin, Zheng Gaofeng
Department of Instrumental and Electrical Engineering, Xiamen University, Xiamen 361102, China.
School of Mechanical and Automotive Engineering, Xiamen University of Technology, Xiamen 361024, China.
Micromachines (Basel). 2018 Aug 24;9(9):427. doi: 10.3390/mi9090427.
The fast and precise direct-printing of micro three-dimensional (3D) structures is the important development trend for micro/nano fabrication technique. A novel method with probe arrays was built up to realize the controllable deposition of 3D electrospun nanofibrous structures. Firstly, several 3D nanofibrous structures were built on a single probe and 2-, 3-probes, which indicated that the probe height and probe interval played a key role on the 3D structure morphology. Then, different stereo nanofibrous structures based on multiprobe arrays were achieved accurately and the effects of processing parameters, including the probe height, probe interval, applied voltage and flow rate on the deposition behaviors of electrospun nanofiber over the probe arrays were investigated. The deposition area of 3D electrospun nanofibrous structures decreased with the increase of probe interval, applied voltage, and flow rate. Several 3D nanofibrous structures of special shapes including convex, triangle wave, inverted cone and complex curved surface were demonstrated by controlling the configuration of probe arrays and electrospinning parameters. This work provides an effective and simple way for the construction of 3D electrospun nanofibrous structures, which has great potentials in various medical and industrial applications.
微三维（3D）结构的快速精确直接打印是微纳制造技术的重要发展趋势。建立了一种基于探针阵列的新方法来实现3D电纺纳米纤维结构的可控沉积。首先，在单个探针以及双探针、三探针上构建了几种3D纳米纤维结构，这表明探针高度和探针间距对3D结构形态起着关键作用。然后，精确实现了基于多探针阵列的不同立体纳米纤维结构，并研究了包括探针高度、探针间距、施加电压和流速在内的工艺参数对电纺纳米纤维在探针阵列上沉积行为的影响。3D电纺纳米纤维结构的沉积面积随探针间距、施加电压和流速的增加而减小。通过控制探针阵列的配置和电纺参数，展示了几种特殊形状的3D纳米纤维结构，包括凸形、三角波、倒锥和复杂曲面。这项工作为构建3D电纺纳米纤维结构提供了一种有效且简单的方法，在各种医疗和工业应用中具有巨大潜力。
