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一名肝硬化患者发生原发性骨髓炎伴菌血症和脓毒症

Primary Osteomyelitis with Bacteremia and Sepsis in a Patient with Cirrhosis.

作者信息

Khatri Akshay, Kanaparthy Naga Sasidhar, Selvaraj Bright Jebaraj, Cho Eunna, El Khoury Marc Y

机构信息

Department of Medicine, New York Medical College at Westchester Medical Center, Valhalla, NY 10595, USA.

Division of Infectious Diseases, New York Medical College at Westchester Medical Center, Valhalla, NY 10595, USA.

出版信息

Case Rep Infect Dis. 2018 Oct 23;2018:3183805. doi: 10.1155/2018/3183805. eCollection 2018.

DOI:10.1155/2018/3183805
PMID:30425866
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6218756/
Abstract

Osteomyelitis is commonly caused by , , , and anaerobes. There have been cases of rare organisms like () being initially overlooked as causes of osteomyelitis. We report a case of an elderly cirrhotic adult male transferred for further management of liver failure, who was subsequently diagnosed with osteomyelitis and sepsis. He had a history of blunt leg trauma, and MRI of the leg revealed osteomyelitis, with a negative workup for other sources of infection. osteomyelitis is reported in less than 100 cases, mainly in pediatric and sickle-cell patients. There are no pathognomonic imaging findings. Lesions may be metastatic, with rapid widespread destruction and exuberant periosteal reaction. is a rare, under recognized cause of osteomyelitis in immune-suppressed adults. Given its pathogenicity, early identification is critical.

摘要

骨髓炎通常由[具体病原体1]、[具体病原体2]、[具体病原体3]和厌氧菌引起。曾有像[罕见病原体名称]([括号内相关说明])这样的罕见病原体导致骨髓炎的病例最初被忽视。我们报告一例老年肝硬化成年男性因肝衰竭转来进一步治疗,随后被诊断为[病原体名称]骨髓炎和败血症。他有腿部钝器伤史,腿部MRI显示骨髓炎,对其他感染源的检查结果为阴性。[病原体名称]骨髓炎报告病例少于100例,主要见于儿童和镰状细胞病患者。没有特异性的影像学表现。病变可能是转移性的,伴有快速广泛破坏和大量骨膜反应。[病原体名称]是免疫抑制成人骨髓炎的一种罕见且未得到充分认识的病因。鉴于其致病性,早期识别至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d0/6218756/96a25d494f6b/CRIID2018-3183805.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d0/6218756/4d922432d1bc/CRIID2018-3183805.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d0/6218756/96a25d494f6b/CRIID2018-3183805.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d0/6218756/4d922432d1bc/CRIID2018-3183805.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d0/6218756/96a25d494f6b/CRIID2018-3183805.003.jpg

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