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早期胸腺癌微创胸腺切除术后的生存结果。

Survival outcomes after minimally invasive thymectomy for early-stage thymic carcinoma.

作者信息

Miyata Ryo, Hamaji Masatsugu, Omasa Mitsugu, Nakagawa Tatsuo, Sumitomo Ryota, Huang Cheng-Long, Ikeda Masaki, Fujinaga Takuji, Shoji Tsuyoshi, Katakura Hiromichi, Motoyama Hideki, Nakajima Daisuke, Ohsumi Akihiro, Menju Toshi, Aoyama Akihiro, Chen-Yoshikawa Toyofumi F, Sato Toshihiko, Sonobe Makoto, Date Hiroshi

机构信息

Department of Thoracic Surgery, Kyoto University Hospital, 54 Kawaharacho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.

Department of Thoracic Surgery, Nishi-Kobe Medical Center, 5-7-1 Koujidai, Nishi-ku, Kobe, 651-2273, Japan.

出版信息

Surg Today. 2019 Apr;49(4):357-360. doi: 10.1007/s00595-018-1740-x. Epub 2018 Nov 14.

Abstract

Minimally invasive surgery (MIS) has occasionally been used for selected patients with thymoma, but there is little information on the MIS approach for thymic carcinoma. The aim of this study was to evaluate survival outcomes after MIS for early-stage (Masaoka stage I-II) thymic carcinoma and thymic neuroendocrine carcinoma. A retrospective chart review of the cases recorded in our multi-institutional database was performed to identify patients who underwent resection for thymic carcinoma between 1995 and 2017. MIS thymectomy was performed in 17 cases (VATS, n = 14; RATS, n = 3. male, 41%; median age, 72 years). The median follow-up period was 32.7 (range 7.4-106) months. The five-year overall survival and relapse-free survival rates were 84.4% and 77.8%, respectively. The present study demonstrated encouraging preliminary results regarding MIS for the treatment of early-stage thymic carcinoma and thymic neuroendocrine carcinoma. Further studies with a larger sample size are required to evaluate the indications for this surgery.

摘要

微创手术(MIS)偶尔用于部分胸腺瘤患者,但关于胸腺癌的微创手术方法的信息很少。本研究的目的是评估早期(Masaoka I-II期)胸腺癌和胸腺神经内分泌癌行微创手术后的生存结果。对我们多机构数据库中记录的病例进行回顾性图表审查,以确定1995年至2017年间接受胸腺癌切除术的患者。17例患者接受了微创胸腺切除术(电视辅助胸腔镜手术,n = 14;机器人辅助胸腔镜手术,n = 3。男性,41%;中位年龄,72岁)。中位随访期为32.7(范围7.4-106)个月。五年总生存率和无复发生存率分别为84.4%和77.8%。本研究显示了关于微创手术治疗早期胸腺癌和胸腺神经内分泌癌的令人鼓舞的初步结果。需要进行更大样本量的进一步研究以评估该手术的适应症。

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