1 Department of Pathology, Microbiology, and Immunology, and.
2 Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee.
Ann Am Thorac Soc. 2018 Nov;15(Suppl 3):S205-S209. doi: 10.1513/AnnalsATS.201806-380AW.
Respiratory syncytial virus (RSV) is a leading cause of hospitalization of infants worldwide each year. Both host and viral factors host factors predispose a subset of what appear to be healthy infants to severe RSV-induced disease. In this review, we outline many genetic and immunologic factors that contribute to airway obstruction that contributes to the severity of RSV infection.
呼吸道合胞病毒（RSV）是导致全球每年婴儿住院的主要原因。宿主和病毒因素都使一部分看似健康的婴儿易患严重的 RSV 感染疾病。在这篇综述中，我们概述了许多导致气道阻塞的遗传和免疫因素，这些因素导致 RSV 感染的严重程度增加。
