Laroche R, Coosemans M, Floch J J, Ndabaneze E
IMTSSA, Marseille.
Med Trop (Mars). 1988 Apr-Jun;48(2):133-8.
Confronted with the extension of chemoresistance of P. falciparum and the gradual renunciation of the fight against the vectors, it is important nowadays to manage better the means of fighting in the zones where chloroquine resistance exists. If preventive treatment of chills by 4-aminoquinolines is still able to realize prevention of mortality, treatment of all confirmed chills by P. falciparum has to combine sulfadoxine-pyrimethamine with quinine or amodiaquine.