Zhang Yi, Yang Zhi-Gang, Yang Meng-Xi, Shi Ke, Li Rui, Diao Kai-Yue, Guo Ying-Kun
Department of Radiology, National Key Laboratory of Biotherapy, West China Hospital.
Department of Radiology.
Medicine (Baltimore). 2018 Nov;97(46):e12983. doi: 10.1097/MD.0000000000012983.
Common atrium (CA) is a rare complex congenital heart disease. The studies of CA are mostly case reports, while few have been done regarding its morphological characteristics. We aimed to determine CA characteristics and diagnostic accuracy in assessing associated malformations in these patients with low-dose dual-source computed tomography (DSCT).Twenty-one pediatric and adolescent CA patients underwent low-dose DSCT. Different ventricular types and associated malformations were assessed. The diagnostic accuracy of DSCT and transthoracic echocardiography (TTE) in evaluating associated malformations were assessed. The effective doses of DSCT were calculated.Patients (n = 21) were divided into CA with biventricular physiology (n = 7) and CA with single ventricle (SV) (n = 14). There were 3 types of SV morphology: single left ventricle (n = 5), single right ventricle (n = 6), and undifferentiated ventricle (n = 3). In all, 22 associated malformations were seen in CA and 56 in CA with SV. DSCT was superior to TTE for detecting intracardiac anomalies (sensitivity: DSCT, 92.31% vs TTE, 76.92%), great vessels anomalies (sensitivity: DSCT, 100.00% vs TTE, 77.50%), and of collateral vessels (sensitivity: DSCT, 100% vs TTE, 20.00%). The estimated mean effective dose was 0.95 ± 0.44 mSv (<1 mSv).This study indicated that low-dose DSCT is an ideal alternative for pediatric and adolescent patients with CA, providing morphological details of CA and associated malformations with high accuracy.
共同心房(CA)是一种罕见的复杂先天性心脏病。关于CA的研究大多为病例报告,而对其形态特征的研究较少。我们旨在通过低剂量双源计算机断层扫描(DSCT)确定这些患者的CA特征及其在评估相关畸形方面的诊断准确性。
21例儿童和青少年CA患者接受了低剂量DSCT检查。评估了不同的心室类型和相关畸形。评估了DSCT和经胸超声心动图(TTE)在评估相关畸形方面的诊断准确性。计算了DSCT的有效剂量。
患者(n = 21)分为具有双心室生理功能的CA(n = 7)和单心室(SV)的CA(n = 14)。SV形态有3种类型:单左心室(n = 5)、单右心室(n = 6)和未分化心室(n = 3)。CA中总共发现22种相关畸形,CA合并SV中发现56种。在检测心内异常(敏感性:DSCT为92.31%,TTE为76.92%)、大血管异常(敏感性:DSCT为100.00%,TTE为77.50%)和侧支血管(敏感性:DSCT为100%,TTE为20.00%)方面,DSCT优于TTE。估计平均有效剂量为0.95±0.44 mSv(<1 mSv)。
本研究表明,低剂量DSCT是儿童和青少年CA患者的理想替代检查方法,能提供CA及其相关畸形的形态学细节,且准确性高。
Medicine (Baltimore). 2018-11
SAGE Open Med Case Rep. 2023-7-29
Int J Cardiol. 2017-2-1
Eur J Radiol. 2016-12
J Cardiovasc Ultrasound. 2016-9