Brocksmith Victoria M, Alradadi Rasha S, Chen Melinda, Eugster Erica A
University of Wisconsin - Madison, American Family Children's Hospital, Department of Pediatrics, 600 Highland Avenue H4/455 CSC, Madison, WI 53792, USA.
Riley Hospital for Children, Department of Pediatric Endocrinology, Indianapolis, IN, USA.
J Pediatr Endocrinol Metab. 2018 Dec 19;31(12):1367-1369. doi: 10.1515/jpem-2018-0250.
Background Limited information is available regarding baseline characteristics of children and adolescents with gender dysphoria (GD). The purpose of this retrospective study was to describe baseline characteristics of pediatric patients referred for GD. Methods A retrospective chart review of pediatric patients with GD referred to the pediatric endocrine clinic between 2002 and 2017 was conducted. Body mass index (BMI) percentiles and z-scores were calculated based on height and weight at the initial visit. Results Seventy-eight patients aged 14.9±2.37 years were identified. Of these, affirmed gender was more often male than female (63% vs. 37%, p=0.024). Although no difference was seen in average BMI z-scores between female to male (FTM) and male to female (MTF) patients, approximately 50% were overweight or obese. A higher incidence of anxiety was present in FTM compared with MTF youth (p=0.05). Fifty-six patients were referred in January 2014 or later, of whom 27% had a history of early expression of GD compared with 55% of those seen prior to 2014 (p=0.061). Conclusions The high prevalence of overweight in TG youth at baseline represents a potential risk for adverse health consequences. There appears to be a change in the age of first manifestation of GD over time.
关于性别焦虑症（GD）儿童和青少年的基线特征，现有信息有限。这项回顾性研究的目的是描述因GD转诊的儿科患者的基线特征。方法：对2002年至2017年间转诊至儿科内分泌诊所的患有GD的儿科患者进行回顾性病历审查。根据初诊时的身高和体重计算体重指数（BMI）百分位数和z评分。结果：共确定了78名年龄为14.9±2.37岁的患者。其中，确认性别的男性多于女性（63%对37%，p=0.024）。虽然女性转男性（FTM）和男性转女性（MTF）患者的平均BMI z评分没有差异，但约50%超重或肥胖。与MTF青少年相比，FTM青少年焦虑症的发病率更高（p=0.05）。56名患者于2014年1月或之后转诊，其中27%有GD早期表达史，而2014年之前转诊的患者这一比例为55%（p=0.061）。结论：TG青少年基线时超重的高患病率代表了不良健康后果的潜在风险。随着时间的推移，GD首次表现的年龄似乎有所变化。
